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NCT07197554 · ClinicalTrials.gov registry record · Phase 1

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

A Phase 1 study of Advanced Solid Tumors and Ewing Sarcoma, sponsored by SEED Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
171
Enrollment target
6
Study locations

NCT07197554 is a Phase 1 study of Advanced Solid Tumors and Ewing Sarcoma that is actively recruiting participants, run by SEED Therapeutics. The registered enrollment target is 171 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (14% lower). The trial reports 6 study locations across 4 states.

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The verdict

NCT07197554, a Phase 1 study of Advanced Solid Tumors and Ewing Sarcoma, is actively recruiting participants, sponsored by SEED Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
171 participants
Enrollment target
6
Study locations

Study Summary

A Phase 1/1B Study of ST-01156 in Patients with Advanced Solid Malignancies

Conditions Studied

Advanced Solid Tumors Ewing Sarcoma Hepatocellular Carcinoma (HCC) Biliary Tract Cancer (BTC)

Interventions

  • DRUG ST-01156

Study Locations (6)

California

  • The City of Hope National Medical Center - Duarte
  • Hoag Memorial Hospital - Newport Beach

Massachusetts

  • Mass General Brigham Cancer Institute - Boston
  • Dana Farber Cancer Institute - Boston

New York

  • Memorial Sloan Kettering Cancer Center - New York

Texas

  • The University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 171 participants
Start Date 2025-12-01
Est. Completion 2029-12-31
Phase Phase 1

Sponsor

SEED Therapeutics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07197554

The ClinicalTrials.gov registry entry for NCT07197554 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 171 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (14% lower). The listed sponsor is SEED Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which ST-01156 is the first listed.

NCT07197554 reports 6 study locations spanning 4 distinct geographic areas - top geographies include California, Massachusetts, New York.

Frequently Asked Questions

What is clinical trial NCT07197554 about?

NCT07197554 is a clinical study titled "A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies". A Phase 1/1B Study of ST-01156 in Patients with Advanced Solid Malignancies

What is the current status of trial NCT07197554?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 171 participants. The study started on 2025-12-01. Estimated completion is 2029-12-31.

What conditions does trial NCT07197554 study?

This clinical trial studies the following conditions: Advanced Solid Tumors, Ewing Sarcoma, Hepatocellular Carcinoma (HCC), Biliary Tract Cancer (BTC).

What interventions are being tested in trial NCT07197554?

The interventions under investigation include: ST-01156 (DRUG).

Who is sponsoring clinical trial NCT07197554?

This trial is sponsored by SEED Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07197554 being conducted?

This trial has 6 study locations across California, Massachusetts, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.