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NCT07184086 · ClinicalTrials.gov registry record · Phase 1
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
A Phase 1 study of Obesity, sponsored by Novo Nordisk A/S.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT07184086: Recruiting Phase 1 study of Obesity, sponsored by Novo Nordisk A/S.
NCT07184086 is a Phase 1 study of Obesity that is actively recruiting participants, run by Novo Nordisk A/S. The registered enrollment target is 80 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07184086, a Phase 1 study of Obesity, is actively recruiting participants, sponsored by Novo Nordisk A/S.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
In this study we will be looking into how CagriSema influences metabolism (the process by which food is used to supply energy for the body) compared to a diet. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors but has previously been tested in humans. The study is split into 2 parts. In the first part of the study, participants will either get CagriSema or a weight loss diet (calorie reduced). In the second part of the study,all participants will get CagriSema. Which treatment participants get in the first part of the study is decided by chance. Like all medicines, the study medicine may have side effects. The study will last for about 1.5 years.
Primary Outcome
Measured as kilojoules (kJ) per day.
Conditions Studied
Interventions
- DRUG CagriSema (Cagrilintide B + semaglutide I)
- BEHAVIORAL Low Energy Diet
Study Locations (2)
Florida
- Advent Health-Res Inst - Orlando
Louisiana
- Pennington Biomed Res Ctr - Baton Rouge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-09-26 |
| Est. Completion | 2027-10-12 |
| Phase | Phase 1 |
What NCT07184086 shows while recruiting
NCT07184086 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which CagriSema (Cagrilintide B + semaglutide I) is the first listed.
NCT07184086 reports a single indexed study location in Florida, Louisiana.
Frequently Asked Questions
What is clinical trial NCT07184086 about?
NCT07184086 is a clinical study titled "A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet". In this study we will be looking into how CagriSema influences metabolism (the process by which food is used to supply energy for the body) compared to a diet. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors but has previously been tested in humans. The stu...
What is the current status of trial NCT07184086?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2025-09-26. Estimated completion is 2027-10-12.
What conditions does trial NCT07184086 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT07184086?
The interventions under investigation include: CagriSema (Cagrilintide B + semaglutide I) (DRUG), Low Energy Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT07184086?
This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07184086 being conducted?
This trial has 2 study locations across Florida, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07184086's enrollment target sits among peer trials
80 546th of 1053 higher than 498 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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