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NCT07172919 · ClinicalTrials.gov registry record · Phase 2
A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation
A Phase 2 study of Advanced Solid Tumors, sponsored by Amgen.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 14
- Enrollment target
- 4
- Study locations
NCT07172919: Recruiting Phase 2 study of Advanced Solid Tumors, sponsored by Amgen.
NCT07172919 is a Phase 2 study of Advanced Solid Tumors that is actively recruiting participants, run by Amgen. The registered enrollment target is 14 participants, below the 199-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (93% lower). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07172919, a Phase 2 study of Advanced Solid Tumors, is actively recruiting participants, sponsored by Amgen.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 14 participants
- Enrollment target
- 4
- Study locations
Study Summary
The primary objective of the study is to evaluate the safety and tolerability of the continuation of sotorasib with or without panitumumab and/or other anti-cancer therapies in participants continuing to derive benefit in Amgen-sponsored protocols.
Primary Outcome
Incidence and severity of TEAEs, clinically significant changes in vital signs, and clinical laboratory tests will be reported as TEAEs.
Conditions Studied
Interventions
- DRUG Sotorasib
- DRUG Panitumumab
Study Locations (4)
Other
- Universitaetsspital Basel - Basel
- Taichung Veterans General Hospital - Taichung
Texas
- University of Texas MD Anderson Cancer Center - Houston
Hokkaido
- National Hospital Organization Hokkaido Cancer Center - Sapporo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2026-01-02 |
| Est. Completion | 2028-01-02 |
| Phase | Phase 2 |
What NCT07172919 shows while recruiting
NCT07172919 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 199-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which Sotorasib is the first listed.
NCT07172919 reports a single indexed study location in Other, Texas, Hokkaido.
Frequently Asked Questions
What is clinical trial NCT07172919 about?
NCT07172919 is a clinical study titled "A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation". The primary objective of the study is to evaluate the safety and tolerability of the continuation of sotorasib with or without panitumumab and/or other anti-cancer therapies in participants continuing to derive benefit in Amgen-sponsored protocols.
What is the current status of trial NCT07172919?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2026-01-02. Estimated completion is 2028-01-02.
What conditions does trial NCT07172919 study?
This clinical trial studies the following conditions: Advanced Solid Tumors.
What interventions are being tested in trial NCT07172919?
The interventions under investigation include: Sotorasib (DRUG), Panitumumab (DRUG).
Who is sponsoring clinical trial NCT07172919?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07172919 being conducted?
This trial has 4 study locations across Texas, Hokkaido. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Advanced Solid Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07172919's enrollment target sits among peer trials
14 134th of 144 higher than 9 of 144 other Advanced Solid Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Advanced Solid Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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