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NCT07139899 · ClinicalTrials.gov registry record
Downstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma
A clinical trial of Severe Asthma, sponsored by Bastiaan Driehuys.
- Recruiting
- Registry status
- 5
- Enrollment target
- 1
- Study location
NCT07139899 is a study of Severe Asthma that is actively recruiting participants, run by Bastiaan Driehuys. The registered enrollment target is 5 participants, below the 3,854-participant average among 9 other Severe Asthma trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07139899, a study of Severe Asthma, is actively recruiting participants, sponsored by Bastiaan Driehuys.
- RECRUITING
- Registry status
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will be identified using CT imaging, and xenon MRI will be used to evaluate ventilation and gas exchange impairments in regions of the lungs corresponding to the airways downstream of mucus plugs.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Hyperpolarized Xenon 129
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2025-11-17 |
| Est. Completion | 2027-09 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07139899
The ClinicalTrials.gov registry entry for NCT07139899 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,854-participant average among 9 other Severe Asthma trials with a reported enrollment target (100% lower). The listed sponsor is Bastiaan Driehuys, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Severe Asthma appearing as the primary indexed condition, and to 1 intervention - of which Hyperpolarized Xenon 129 is the first listed.
NCT07139899 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT07139899 about?
NCT07139899 is a clinical study titled "Downstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma". In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will be identified using CT imaging, and xenon MRI will be used to evaluate ventilation and gas exchange impairments in regions of the lungs corr...
What is the current status of trial NCT07139899?
This trial is currently recruiting. The enrollment target is 5 participants. The study started on 2025-11-17. Estimated completion is 2027-09.
What conditions does trial NCT07139899 study?
This clinical trial studies the following conditions: Severe Asthma.
What interventions are being tested in trial NCT07139899?
The interventions under investigation include: Hyperpolarized Xenon 129 (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07139899?
This trial is sponsored by Bastiaan Driehuys, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07139899 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Severe Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
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Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Severe Asthma
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-
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
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-
Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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