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NCT00501826 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
A Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT00501826: Recruiting Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma, sponsored by M.D. Anderson Cancer Center.
NCT00501826 is a Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 160 participants, below the 212-participant average among 5 other T Acute Lymphoblastic Leukemia trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00501826, a Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, cytarabine, mercaptopurine, prednisone, pegaspargase, nelarabine, and venetoclax work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Primary Outcome
The sample size will provide an estimate of relapse rate at 3 years with a 95% confidence interval of width +/- 10%.
Conditions Studied
Interventions
- DRUG Cyclophosphamide
- DRUG Doxorubicin Hydrochloride
- DRUG Dexamethasone
- DRUG Cytarabine
- DRUG Mercaptopurine
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2007-07-11 |
| Est. Completion | 2026-10-31 |
| Phase | Phase 2 |
What NCT00501826 shows while recruiting
NCT00501826 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 212-participant average among 5 other T Acute Lymphoblastic Leukemia trials with a reported enrollment target (25% lower).
The record links to 2 conditions, with T Acute Lymphoblastic Leukemia appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.
NCT00501826 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00501826 about?
NCT00501826 is a clinical study titled "Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma". This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate,...
What is the current status of trial NCT00501826?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2007-07-11. Estimated completion is 2026-10-31.
What conditions does trial NCT00501826 study?
This clinical trial studies the following conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma.
What interventions are being tested in trial NCT00501826?
The interventions under investigation include: Cyclophosphamide (DRUG), Doxorubicin Hydrochloride (DRUG), Dexamethasone (DRUG), Cytarabine (DRUG), Mercaptopurine (DRUG).
Who is sponsoring clinical trial NCT00501826?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00501826 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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