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NCT00501826 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

A Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
160
Enrollment target
1
Study location

NCT00501826 is a Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 160 participants, below the 212-participant average among 5 other T Acute Lymphoblastic Leukemia trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00501826, a Phase 2 study of T Acute Lymphoblastic Leukemia and T Lymphoblastic Lymphoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, cytarabine, mercaptopurine, prednisone, pegaspargase, nelarabine, and venetoclax work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Doxorubicin Hydrochloride
  • DRUG Dexamethasone
  • DRUG Cytarabine
  • DRUG Mercaptopurine

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2007-07-11
Est. Completion 2026-10-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00501826

The ClinicalTrials.gov registry entry for NCT00501826 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 212-participant average among 5 other T Acute Lymphoblastic Leukemia trials with a reported enrollment target (25% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with T Acute Lymphoblastic Leukemia appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT00501826 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT00501826 about?

NCT00501826 is a clinical study titled "Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma". This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate,...

What is the current status of trial NCT00501826?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2007-07-11. Estimated completion is 2026-10-31.

What conditions does trial NCT00501826 study?

This clinical trial studies the following conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma.

What interventions are being tested in trial NCT00501826?

The interventions under investigation include: Cyclophosphamide (DRUG), Doxorubicin Hydrochloride (DRUG), Dexamethasone (DRUG), Cytarabine (DRUG), Mercaptopurine (DRUG).

Who is sponsoring clinical trial NCT00501826?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00501826 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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