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NCT04649008 · ClinicalTrials.gov registry record · Early Phase 1

Localizing Epileptic Networks Using MRI and iEEG

A Early Phase 1 study of Epilepsy and Epilepsy, Temporal Lobe, sponsored by University of Pennsylvania.

Recruiting
Registry status
Early Phase 1
Development phase
290
Enrollment target
1
Study location

NCT04649008 is a Early Phase 1 study of Epilepsy and Epilepsy, Temporal Lobe that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 290 participants, below the 951-participant average among 160 other Epilepsy trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04649008, a Early Phase 1 study of Epilepsy and Epilepsy, Temporal Lobe, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
Early Phase 1
Development phase
290 participants
Enrollment target
1
Study location

Study Summary

Upon successful completion of this study, the investigators expect the study's contribution to be the development of noninvasive imaging biomarkers to predict IEEG functional dynamics and epilepsy surgical outcomes. Findings from the present study may inform current and new therapies to map and alter seizure spread, and pave the way for less invasive, better- targeted, patient-specific interventions with improved surgical outcomes. This research is relevant to public health because over 20 million people worldwide suffer from focal drug-resistant epilepsy and are potential candidates for cure with epilepsy surgical interventions.

Interventions

  • DIAGNOSTIC_TEST 3T Magnetic Resonance Imaging
  • DIAGNOSTIC_TEST Intracranial electroencephalography recordings
  • DIAGNOSTIC_TEST 7T Magnetic Resonance Imaging

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 290 participants
Start Date 2021-03-01
Est. Completion 2027-02-28
Phase Early Phase 1

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT04649008

The ClinicalTrials.gov registry entry for NCT04649008 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 290 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 951-participant average among 160 other Epilepsy trials with a reported enrollment target (70% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Epilepsy appearing as the primary indexed condition, and to 3 interventions - of which 3T Magnetic Resonance Imaging is the first listed.

NCT04649008 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04649008 about?

NCT04649008 is a clinical study titled "Localizing Epileptic Networks Using MRI and iEEG". Upon successful completion of this study, the investigators expect the study's contribution to be the development of noninvasive imaging biomarkers to predict IEEG functional dynamics and epilepsy surgical outcomes. Findings from the present study may inform current and new therapies to map and alte...

What is the current status of trial NCT04649008?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 290 participants. The study started on 2021-03-01. Estimated completion is 2027-02-28.

What conditions does trial NCT04649008 study?

This clinical trial studies the following conditions: Epilepsy, Epilepsy, Temporal Lobe, Epilepsy Intractable.

What interventions are being tested in trial NCT04649008?

The interventions under investigation include: 3T Magnetic Resonance Imaging (DIAGNOSTIC_TEST), Intracranial electroencephalography recordings (DIAGNOSTIC_TEST), 7T Magnetic Resonance Imaging (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04649008?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04649008 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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