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NCT07102641 · ClinicalTrials.gov registry record · Phase 4

Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies

A Phase 4 study of Post Operative Pain and Cesarean Delivery, sponsored by Thomas Jefferson University.

Recruiting
Registry status
Phase 4
Development phase
825
Enrollment target
1
Study location

NCT07102641 is a Phase 4 study of Post Operative Pain and Cesarean Delivery that is actively recruiting participants, run by Thomas Jefferson University. The registered enrollment target is 825 participants, above the 222-participant average among 56 other Post Operative Pain trials with a reported enrollment target (272% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT07102641, a Phase 4 study of Post Operative Pain and Cesarean Delivery, is actively recruiting participants, sponsored by Thomas Jefferson University.

RECRUITING
Registry status
Phase 4
Development phase
825 participants
Enrollment target
1
Study location

Study Summary

Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are the preferred first-line therapies. There is no standard practice, however, on best dosing schedules (ie staggered or different time v. simultaneous or same time). This protocol describes a randomized clinical trial aimed to determine whether staggered dosing of acetaminophen and NSAIDs in superior to simultaneous dosing in controlling post-cesarean pain.

Interventions

  • DRUG Acetaminophen
  • DRUG NSAID (Ketorolac/Ibuprofen)

Study Locations (1)

Pennsylvania

  • Thomas Jefferson University Hospital - Philadelphia

Trial Details

FieldValue
Enrollment Target 825 participants
Start Date 2025-08-26
Est. Completion 2027-12
Phase Phase 4

Sponsor

Thomas Jefferson University

292 total trials

What the Registry Record Tells You About NCT07102641

The ClinicalTrials.gov registry entry for NCT07102641 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 825 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 222-participant average among 56 other Post Operative Pain trials with a reported enrollment target (272% higher). The listed sponsor is Thomas Jefferson University, which has 292 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Post Operative Pain appearing as the primary indexed condition, and to 2 interventions - of which Acetaminophen is the first listed.

NCT07102641 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT07102641 about?

NCT07102641 is a clinical study titled "Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies". Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal ...

What is the current status of trial NCT07102641?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 825 participants. The study started on 2025-08-26. Estimated completion is 2027-12.

What conditions does trial NCT07102641 study?

This clinical trial studies the following conditions: Post Operative Pain, Cesarean Delivery, Postpartum Pain, Postpartum Comfort, NSAIDs.

What interventions are being tested in trial NCT07102641?

The interventions under investigation include: Acetaminophen (DRUG), NSAID (Ketorolac/Ibuprofen) (DRUG).

Who is sponsoring clinical trial NCT07102641?

This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07102641 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.