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NCT07102641 · ClinicalTrials.gov registry record · Phase 4
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
A Phase 4 study of Postoperative Pain and Cesarean Delivery, sponsored by Thomas Jefferson University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 825
- Enrollment target
- 1
- Study location
NCT07102641: Recruiting Phase 4 study of Postoperative Pain and Cesarean Delivery, sponsored by Thomas Jefferson University.
NCT07102641 is a Phase 4 study of Postoperative Pain and Cesarean Delivery that is actively recruiting participants, run by Thomas Jefferson University. The registered enrollment target is 825 participants, above the 225-participant average among 120 other Postoperative Pain trials with a reported enrollment target (267% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07102641, a Phase 4 study of Postoperative Pain and Cesarean Delivery, is actively recruiting participants, sponsored by Thomas Jefferson University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 825 participants
- Enrollment target
- 1
- Study location
Study Summary
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are the preferred first-line therapies. There is no standard practice, however, on best dosing schedules (ie staggered or different time v. simultaneous or same time). This protocol describes a randomized clinical trial aimed to determine whether staggered dosing of acetaminophen and NSAIDs in superior to simultaneous dosing in controlling post-cesarean pain.
Primary Outcome
Visual analog pain score (VAS) with movement. Scale ranges from 0-10 with 0 indicating no pain and 10 indicating worst possible pain
Conditions Studied
Interventions
- DRUG Acetaminophen
- DRUG NSAID (Ketorolac/Ibuprofen)
Study Locations (1)
Pennsylvania
- Thomas Jefferson University Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 825 participants |
| Start Date | 2025-08-26 |
| Est. Completion | 2027-12 |
| Phase | Phase 4 |
What NCT07102641 shows while recruiting
NCT07102641 is an interventional study that assigns participants to a tested intervention. The registered 825 participants enrollment target is mid-sized for trials with a published cap, above the 225-participant average among 120 other Postoperative Pain trials with a reported enrollment target (267% higher).
The record links to 6 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Acetaminophen is the first listed.
NCT07102641 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07102641 about?
NCT07102641 is a clinical study titled "Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies". Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal ...
What is the current status of trial NCT07102641?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 825 participants. The study started on 2025-08-26. Estimated completion is 2027-12.
What conditions does trial NCT07102641 study?
This clinical trial studies the following conditions: Postoperative Pain, Cesarean Delivery, Postpartum Pain, Postpartum Comfort, NSAIDs.
What interventions are being tested in trial NCT07102641?
The interventions under investigation include: Acetaminophen (DRUG), NSAID (Ketorolac/Ibuprofen) (DRUG).
Who is sponsoring clinical trial NCT07102641?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07102641 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07102641's enrollment target sits among peer trials
825 6th of 120 higher than 115 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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