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NCT07097506 · ClinicalTrials.gov registry record · Phase 2
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
A Phase 2 study of Obesity and MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07097506 is a Phase 2 study of Obesity and MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 40 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07097506, a Phase 2 study of Obesity and MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control. Ketones are a type of energy source made by the body during times of weight loss, low carbohydrate intake and starvation. People enrolled in this study will be randomly assigned (by chance, like the flip of a coin) to one of two groups: Group 1: Ketone ester drink consumed daily for 6 weeks. Group 2: Placebo drink consumed daily for 6 weeks.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester)
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-09-26 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07097506
The ClinicalTrials.gov registry entry for NCT07097506 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (95% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07097506 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT07097506 about?
NCT07097506 is a clinical study titled "Effect of Ketone Esters on Liver Fat Content and Metabolic Function". The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control. Ketones are a type of energy source made by the body during times of weight loss, low carbohydrate intake and starvation. People enrolled in this study wil...
What is the current status of trial NCT07097506?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2025-09-26. Estimated completion is 2027-12-31.
What conditions does trial NCT07097506 study?
This clinical trial studies the following conditions: Obesity, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight (BMI > 25).
What interventions are being tested in trial NCT07097506?
The interventions under investigation include: Placebo (OTHER), bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester) (DRUG).
Who is sponsoring clinical trial NCT07097506?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07097506 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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