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NCT07083583 · ClinicalTrials.gov registry record
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
A clinical trial of Bleeding and Iron, sponsored by Nicoletta C Machin.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT07083583: Recruiting study of Bleeding and Iron, sponsored by Nicoletta C Machin.
NCT07083583 is a study of Bleeding and Iron that is actively recruiting participants, run by Nicoletta C Machin. The registered enrollment target is 40 participants, below the 1,483-participant average among 23 other Bleeding trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07083583, a study of Bleeding and Iron, is actively recruiting participants, sponsored by Nicoletta C Machin.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin \<50ng/dL). Subjects will undergo baseline bleeding assessments, quality-of-life measures, and laboratory tests before receiving standard-of-care IV iron. Follow-up blood work and questionnaires will be conducted post-replacement to assess for changes
Primary Outcome
Change in bleeding severity 3 months after IV iron replacement, assessed using the ISTH-BAT (International Society on Thrombosis and Haemostasis Bleeding Assessment Tool). ISTH-BAT: Score range 0-56; higher scores indicate greater bleeding severity. Safety Issue: No
Conditions Studied
Interventions
- DRUG IV Iron (standard of care)
Study Locations (1)
Pennsylvania
- Hemophilia Center of Western Pennsylvania - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-08-08 |
| Est. Completion | 2027-10-01 |
What NCT07083583 shows while recruiting
NCT07083583 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,483-participant average among 23 other Bleeding trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Bleeding appearing as the primary indexed condition, and to 1 intervention - of which IV Iron (standard of care) is the first listed.
NCT07083583 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07083583 about?
NCT07083583 is a clinical study titled "Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders". This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin \<50ng/dL). Subjects will undergo baseline bleeding assessments, quality-of-life measures, and l...
What is the current status of trial NCT07083583?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2025-08-08. Estimated completion is 2027-10-01.
What conditions does trial NCT07083583 study?
This clinical trial studies the following conditions: Bleeding, Iron, Bleeding Disorders, Platelet.
What interventions are being tested in trial NCT07083583?
The interventions under investigation include: IV Iron (standard of care) (DRUG).
Who is sponsoring clinical trial NCT07083583?
This trial is sponsored by Nicoletta C Machin, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07083583 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bleeding
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07083583's enrollment target sits among peer trials
40 22nd of 23 higher than 1 of 23 other Bleeding trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bleeding trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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