Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04598750 · ClinicalTrials.gov registry record
The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia
A clinical trial of Bleeding and Neonatal Thrombocytopenia, sponsored by Karolinska Institutet.
- Recruiting
- Registry status
- 250
- Enrollment target
- 8
- Study locations
NCT04598750: Recruiting study of Bleeding and Neonatal Thrombocytopenia, sponsored by Karolinska Institutet.
NCT04598750 is a study of Bleeding and Neonatal Thrombocytopenia that is actively recruiting participants, run by Karolinska Institutet. The registered enrollment target is 250 participants, below the 1,474-participant average among 23 other Bleeding trials with a reported enrollment target (83% lower). The trial reports 8 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04598750, a study of Bleeding and Neonatal Thrombocytopenia, is actively recruiting participants, sponsored by Karolinska Institutet.
- RECRUITING
- Registry status
- 250 participants
- Enrollment target
- 8
- Study locations
Study Summary
This is a prospective observational study designed to evaluate Immature Platelet Fraction or Immature Platelet Count and Platelet Function Analyzer-100/200 Closure Time-ADP (in vitro bleeding time) as markers of bleeding risk in thrombocytopenic preterm neonates admitted to the Neonatal Intensive Care Unit.
Primary Outcome
NeoBAT scores will include any bleeding since the last platelet count or over the prior 24 hours, whichever is shortest. This will serve to correlate bleeding scores (NeoBAT) with platelet counts, IPF% and IPC, PFA-100/200 CT-ADP, and to quantify changes in response to platelet transfusions. The scale is 1 to 4 with 1 being Minor Hemorrhage and 4 being Severe Hemorrhage.
Conditions Studied
Study Locations (8)
Other
- Amsterdam University Medical Centre - Amsterdam
- Leiden University Medical Center - Leiden
- Karolinska University Hospital Huddinge campus - Huddinge
- Karolinska University Hospital Solna campus, Astrid Lindgren Children's Hospital - Stockholm
Massachusetts
- Boston Children's Hospital - Boston
- Beth Israel Deaconess Medical Center - Boston
Utah
- Intermountain Medical Center - Murray
- Utah Valley Hospital - Provo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2021-06-15 |
| Est. Completion | 2025-12-31 |
What NCT04598750 shows while recruiting
NCT04598750 is an observational study that tracks outcomes without assigning an intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 1,474-participant average among 23 other Bleeding trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Bleeding appearing as the primary indexed condition, and to 0 interventions.
NCT04598750 lists 8 locations in 3 states (Other, Massachusetts, Utah).
Frequently Asked Questions
What is clinical trial NCT04598750 about?
NCT04598750 is a clinical study titled "The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia". This is a prospective observational study designed to evaluate Immature Platelet Fraction or Immature Platelet Count and Platelet Function Analyzer-100/200 Closure Time-ADP (in vitro bleeding time) as markers of bleeding risk in thrombocytopenic preterm neonates admitted to the Neonatal Intensive Ca...
What is the current status of trial NCT04598750?
This trial is currently recruiting. The enrollment target is 250 participants. The study started on 2021-06-15. Estimated completion is 2025-12-31.
What conditions does trial NCT04598750 study?
This clinical trial studies the following conditions: Bleeding, Neonatal Thrombocytopenia.
Who is sponsoring clinical trial NCT04598750?
This trial is sponsored by Karolinska Institutet, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04598750 being conducted?
This trial has 8 study locations across Massachusetts, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bleeding
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04598750's enrollment target sits among peer trials
250 11th of 23 higher than 13 of 23 other Bleeding trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bleeding trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery
RECRUITING · Phase 2
-
Quantra Point-of-Care Hemostasis Monitoring
RECRUITING · NA
-
Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device
RECRUITING · Phase 4
-
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
RECRUITING · Phase 3
-
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
RECRUITING
-
Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00483249 · 250 participants · NA
Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
- NCT00777712 · 250 participants
Mechanisms Underlying Impaired Diabetic Wound Healing
- NCT01451502 · 250 participants · NA
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units
- NCT01771718 · 250 participants
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI