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2026 data Public-data reference. official source

Bleeding

Open-data reference.

24 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 3,200 participants

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Icahn School of Medicine at Mount Sinai

NCT04045665

RECRUITING NA 666 participants

Quantra Point-of-Care Hemostasis Monitoring

The Cleveland Clinic

NCT06328647

RECRUITING Phase 2 394 participants

Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery

Kristen Ban

NCT06657924

RECRUITING 250 participants

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia

Karolinska Institutet

NCT04598750

RECRUITING Phase 2 140 participants

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

Northwell Health

NCT07032792

RECRUITING Phase 4 128 participants

Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device

Columbia University

NCT06655376

RECRUITING 40 participants

Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders

Nicoletta C Machin

NCT07083583

ACTIVE NOT RECRUITING 19,114 participants

Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)

Anne Murray

NCT07224347

ACTIVE NOT RECRUITING NA 3,000 participants

CHAMPION-AF Clinical Trial

Boston Scientific Corporation

NCT04394546

ACTIVE NOT RECRUITING NA 2,650 participants

Amplatzer Amulet LAAO vs. NOAC

Abbott Medical Devices

NCT04226547

ACTIVE NOT RECRUITING NA 1,857 participants

SIMPLAAFY Clinical Trial

Boston Scientific Corporation

NCT06521463

ACTIVE NOT RECRUITING 610 participants

Amulet™ ADVANCE LAA

Abbott Medical Devices

NCT05997446

COMPLETED NA 561 participants

LEAVE Safe With DOACs

University of Massachusetts, Worcester

NCT04068727

COMPLETED NA 411 participants

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)

Medical Compression Systems

NCT00358735

COMPLETED NA 236 participants

Efficacy and Safety of HemoStyp as an Adjunct for Management of Secondary Hemostasis in the Operative Setting

United Health Products

NCT03654560

COMPLETED Phase 4 208 participants

Transfusion of Pathogen Reduced Cryoprecipitated Fibrinogen to Expedite Product Availability in Perioperative Bleeding

Weill Medical College of Cornell University

NCT05711524

COMPLETED 125 participants

Obsidio™ Conformable Embolic Registry

Boston Scientific Corporation

NCT06170619

COMPLETED Phase 4 109 participants

Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users

Oregon Health and Science University

NCT02903121

COMPLETED Phase 2 108 participants

A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects

Portola Pharmaceuticals

NCT03310021

COMPLETED Phase 4 106 participants

PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

Mayo Clinic

NCT02557672

COMPLETED 85 participants

Peri-device Leakage Closure After LAAO

Cardiovascular Center Frankfurt

NCT04590898

COMPLETED Phase 3 80 participants

A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban

Portola Pharmaceuticals

NCT02220725

COMPLETED Phase 1 40 participants

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

International Partnership for Microbicides

NCT05041699

COMPLETED 33 participants

Thromboelastography in Non-elective Cesarean Delivery

Stanford University

NCT01514591

Phase Distribution

PhaseTrial count
Early Phase 1 1
Phase 2 3
Phase 3 2
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Bleeding Trial Landscape

ClinicalTrials.gov lists 24 US studies indexed under Bleeding, and 7 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Bleeding shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Bleeding is led by Boston Scientific Corporation with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Bleeding?

PlainTrial tracks 24 US clinical trials for Bleeding, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Bleeding?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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