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NCT05607719 · ClinicalTrials.gov registry record · Phase 2
Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD
A Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by University of Miami.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05607719: Recruiting Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by University of Miami.
NCT05607719 is a Phase 2 study of Chronic Obstructive Pulmonary Disease that is actively recruiting participants, run by University of Miami. The registered enrollment target is 30 participants, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05607719, a Phase 2 study of Chronic Obstructive Pulmonary Disease, is actively recruiting participants, sponsored by University of Miami.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The study objective is to determine whether an ICS added for 4 weeks to a baseline treatment with a Long-Acting Beta-adrenergic Agonist (LABA) and Long-Acting Muscarinic Antagonist (LAMA) combination improves pulmonary vascular endothelial function as assessed by the vasodilator response to inhaled albuterol (endothelium-dependent vasodilation) in stable COPD patients treated with a LABA/LAMA without an ICS for at least one month.
Primary Outcome
Echocardiographic assessment of PVR before and after inhalation of 180 μg albuterol as a test of endothelial function
Conditions Studied
Interventions
- DRUG Bevespi
- DRUG Bretzri
Study Locations (1)
Florida
- University of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-04-11 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 2 |
What NCT05607719 shows while recruiting
NCT05607719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions - of which Bevespi is the first listed.
NCT05607719 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05607719 about?
NCT05607719 is a clinical study titled "Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD". The study objective is to determine whether an ICS added for 4 weeks to a baseline treatment with a Long-Acting Beta-adrenergic Agonist (LABA) and Long-Acting Muscarinic Antagonist (LAMA) combination improves pulmonary vascular endothelial function as assessed by the vasodilator response to inhaled ...
What is the current status of trial NCT05607719?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2023-04-11. Estimated completion is 2026-12-31.
What conditions does trial NCT05607719 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease.
What interventions are being tested in trial NCT05607719?
The interventions under investigation include: Bevespi (DRUG), Bretzri (DRUG).
Who is sponsoring clinical trial NCT05607719?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05607719 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Obstructive Pulmonary Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05607719's enrollment target sits among peer trials
30 67th of 86 higher than 16 of 86 other Chronic Obstructive Pulmonary Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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