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NCT06967259 · ClinicalTrials.gov registry record · Phase 1

ENA-001 for Opioid Induced Respiratory Depression

A Phase 1 study of Respiratory Depression, sponsored by Enalare Therapeutics.

Active
Registry status
Phase 1
Development phase
36
Enrollment target
2
Study locations

NCT06967259 is a Phase 1 study of Respiratory Depression that is active but no longer recruiting, run by Enalare Therapeutics. The registered enrollment target is 36 participants, below the 42-participant average among 4 other Respiratory Depression trials with a reported enrollment target (14% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06967259, a Phase 1 study of Respiratory Depression, is active but no longer recruiting, sponsored by Enalare Therapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
36 participants
Enrollment target
2
Study locations

Study Summary

This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.

Conditions Studied

Respiratory Depression

Interventions

  • DRUG Placebo Comparator
  • DRUG ENA-001

Study Locations (2)

Kansas

  • Dr. Vince Clinical Research - Overland Park

New Jersey

  • Clinilabs - Eatontown

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2025-05-14
Est. Completion 2026-12-30
Phase Phase 1

Sponsor

Enalare Therapeutics

1 total trials

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What the Registry Record Tells You About NCT06967259

The ClinicalTrials.gov registry entry for NCT06967259 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 42-participant average among 4 other Respiratory Depression trials with a reported enrollment target (14% lower). The listed sponsor is Enalare Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Respiratory Depression appearing as the primary indexed condition, and to 2 interventions - of which Placebo Comparator is the first listed.

NCT06967259 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Kansas, New Jersey.

Frequently Asked Questions

What is clinical trial NCT06967259 about?

NCT06967259 is a clinical study titled "ENA-001 for Opioid Induced Respiratory Depression". This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.

What is the current status of trial NCT06967259?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2025-05-14. Estimated completion is 2026-12-30.

What conditions does trial NCT06967259 study?

This clinical trial studies the following conditions: Respiratory Depression.

What interventions are being tested in trial NCT06967259?

The interventions under investigation include: Placebo Comparator (DRUG), ENA-001 (DRUG).

Who is sponsoring clinical trial NCT06967259?

This trial is sponsored by Enalare Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06967259 being conducted?

This trial has 2 study locations across Kansas, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.