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NCT06800703 · ClinicalTrials.gov registry record
Opioid Use Disorder and Pain
A clinical trial of Opioid Use Disorder and Healthy Controls Group - Age and Sex-matched, sponsored by Yale University.
- Recruiting
- Registry status
- 180
- Enrollment target
- 1
- Study location
NCT06800703: Recruiting study of Opioid Use Disorder and Healthy Controls Group - Age and Sex-matched, sponsored by Yale University.
NCT06800703 is a study of Opioid Use Disorder and Healthy Controls Group - Age and Sex-matched that is actively recruiting participants, run by Yale University. The registered enrollment target is 180 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06800703, a study of Opioid Use Disorder and Healthy Controls Group - Age and Sex-matched, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to characterize the brain processes of pain avoidance learning dysfunctions in individuals with opioid use disorder (OUD). The main questions it aims to answer are: Compared with healthy controls, do those with OUD exhibit impaired avoidance learning in response to pain? What are the brain processes that are associated with this avoidance learning dysfunction? Do these brain processes serve to predict future use or relapse? Researchers will compare those with OUD and healthy controls to determine avoidance learning dysfunction and its relationship with opioid use. Participants will be performing a learning task inside an fMRI scanner. Those with OUD will also be followed up for a year to determine future opioid use.
Primary Outcome
Task performance measure of avoidance learning, quantified by response time and performance accuracy. Those with OUD are expected to have lower performance accuracy, lower learning rates, and higher response time during avoidance learning relative to healthy controls
Conditions Studied
Interventions
- BEHAVIORAL follow up interviews for 12 months to determine opioid use
Study Locations (1)
Connecticut
- Connecticut Mental Health Center, S105 - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2025-02-04 |
| Est. Completion | 2028-01 |
What NCT06800703 shows while recruiting
NCT06800703 is an observational study that tracks outcomes without assigning an intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which follow up interviews for 12 months to determine opioid use is the first listed.
NCT06800703 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06800703 about?
NCT06800703 is a clinical study titled "Opioid Use Disorder and Pain". The goal of this observational study is to characterize the brain processes of pain avoidance learning dysfunctions in individuals with opioid use disorder (OUD). The main questions it aims to answer are: Compared with healthy controls, do those with OUD exhibit impaired avoidance learning in respo...
What is the current status of trial NCT06800703?
This trial is currently recruiting. The enrollment target is 180 participants. The study started on 2025-02-04. Estimated completion is 2028-01.
What conditions does trial NCT06800703 study?
This clinical trial studies the following conditions: Opioid Use Disorder, Healthy Controls Group - Age and Sex-matched.
What interventions are being tested in trial NCT06800703?
The interventions under investigation include: follow up interviews for 12 months to determine opioid use (BEHAVIORAL).
Who is sponsoring clinical trial NCT06800703?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06800703 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06800703's enrollment target sits among peer trials
180 100th of 257 higher than 155 of 257 other Opioid Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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