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NCT06802276 · ClinicalTrials.gov registry record · NA
Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production
A NA study of Gastrointestinal Microbiome and Hydrogen Sulfide, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT06802276: Recruiting NA study of Gastrointestinal Microbiome and Hydrogen Sulfide, sponsored by University of Colorado, Denver.
NCT06802276 is a NA study of Gastrointestinal Microbiome and Hydrogen Sulfide that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 25 participants, below the 185-participant average among 6 other Gastrointestinal Microbiome trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06802276, a NA study of Gastrointestinal Microbiome and Hydrogen Sulfide, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the ability of a wearable Smart Underwear prototype device to quantify diet-induced changes in gut microbial hydrogen sulfide (H₂S) production. The core design is a single-site, 2-period, crossover feeding study with 6-day diet periods and an approximately 11-day washout period. Participants are fed each of two isocaloric diets designed to contrast gut microbial H₂S production (i.e., a high cysteine vs. low cysteine diet), in a random order.
Primary Outcome
Participants will be instructed to wear the Smart Underwear device for all waking hours during the baseline and feeding periods except for bathing and exercise. The Smart Underwear device does not need to be worn while sleeping due to the decreased frequency of flatus. Participants will be warned by the Smart Underwear device if the device is not worn for at least 12 hours per day or if the device detects that it is being worn incorrectly. Aggregate metrics from the device will be included in ei
Conditions Studied
Interventions
- OTHER Low Cysteine Diet
- OTHER High Cysteine Diet
Study Locations (1)
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2025-05-21 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT06802276 shows while recruiting
NCT06802276 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 185-participant average among 6 other Gastrointestinal Microbiome trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Gastrointestinal Microbiome appearing as the primary indexed condition, and to 2 interventions - of which Low Cysteine Diet is the first listed.
NCT06802276 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06802276 about?
NCT06802276 is a clinical study titled "Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production". The purpose of this study is to evaluate the ability of a wearable Smart Underwear prototype device to quantify diet-induced changes in gut microbial hydrogen sulfide (H₂S) production. The core design is a single-site, 2-period, crossover feeding study with 6-day diet periods and an approximately 11...
What is the current status of trial NCT06802276?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2025-05-21. Estimated completion is 2027-06-30.
What conditions does trial NCT06802276 study?
This clinical trial studies the following conditions: Gastrointestinal Microbiome, Hydrogen Sulfide.
What interventions are being tested in trial NCT06802276?
The interventions under investigation include: Low Cysteine Diet (OTHER), High Cysteine Diet (OTHER).
Who is sponsoring clinical trial NCT06802276?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06802276 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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