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NCT05692024 · ClinicalTrials.gov registry record · Phase 1

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

A Phase 1 study of Colorectal Cancer and Fibrosis, Liver, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
Phase 1
Development phase
80
Enrollment target
1
Study location

NCT05692024 is a Phase 1 study of Colorectal Cancer and Fibrosis, Liver that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 80 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05692024, a Phase 1 study of Colorectal Cancer and Fibrosis, Liver, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
Phase 1
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.

Interventions

  • DRUG Placebo
  • DRUG Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule.

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-03-21
Est. Completion 2027-12-01
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT05692024

The ClinicalTrials.gov registry entry for NCT05692024 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05692024 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05692024 about?

NCT05692024 is a clinical study titled "COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER". This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.

What is the current status of trial NCT05692024?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2024-03-21. Estimated completion is 2027-12-01.

What conditions does trial NCT05692024 study?

This clinical trial studies the following conditions: Colorectal Cancer, Fibrosis, Liver, Gastrointestinal Microbiome, Stenosis, Coffee.

What interventions are being tested in trial NCT05692024?

The interventions under investigation include: Placebo (DRUG), Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule. (DRUG).

Who is sponsoring clinical trial NCT05692024?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05692024 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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