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NCT03876223 · ClinicalTrials.gov registry record
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
A clinical trial of Heart Failure With Preserved Ejection Fraction (HFPEF) and Coronary Microvascular Dysfunction, sponsored by Cedars-Sinai Medical Center.
- Recruiting
- Registry status
- 180
- Enrollment target
- 2
- Study locations
NCT03876223 is a study of Heart Failure With Preserved Ejection Fraction (HFPEF) and Coronary Microvascular Dysfunction that is actively recruiting participants, run by Cedars-Sinai Medical Center. The registered enrollment target is 180 participants, below the 200-participant average among 9 other Heart Failure With Preserved Ejection Fraction (HFPEF) trials with a reported enrollment target (10% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT03876223, a study of Heart Failure With Preserved Ejection Fraction (HFPEF) and Coronary Microvascular Dysfunction, is actively recruiting participants, sponsored by Cedars-Sinai Medical Center.
- RECRUITING
- Registry status
- 180 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to examine small vessel disease (a condition in which the small arteries in the heart become narrowed). The investigators want to know how the small vessel disease contributes to pre-HFpEF (a condition with inadequate heart muscle function in the setting of preserved muscle pumping) and to better identify potential treatment for prevention of HFpEF. The main procedures of this study include up to 2 clinic visits (initial visit and a second clinical visit only if participants are unable to complete all research procedures at the initial visit); a 6-week phone interview visit, 4 quarterly follow-up phone interview visits in year 1; year 1 follow up cardiac MRI based on availability and ongoing annual follow-up phone interview visits to track progress. If participants choose to take part in this study, participants direct participation will end after 1 year, participants will then have the option of participating in ongoing annual check-in calls. Participants will be asked to undergo a physical exam and provide a completed medical history; complete a Cardiovascular (or Cardiac) Magnetic Resonance Imaging (CMRI) with contrast agent; complete questionnaires to describe heart symptoms and overall quality of life status; undergo blood draws to provide blood samples for research testing, and allow the study team to have access to medical records.
Conditions Studied
Study Locations (2)
California
- Cedars-Sinai Medical Center - Los Angeles
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2019-07-24 |
| Est. Completion | 2026-02-28 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03876223
The ClinicalTrials.gov registry entry for NCT03876223 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 200-participant average among 9 other Heart Failure With Preserved Ejection Fraction (HFPEF) trials with a reported enrollment target (10% lower). The listed sponsor is Cedars-Sinai Medical Center, which has 339 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Heart Failure With Preserved Ejection Fraction (HFPEF) appearing as the primary indexed condition, and to 0 interventions.
NCT03876223 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Florida.
Frequently Asked Questions
What is clinical trial NCT03876223 about?
NCT03876223 is a clinical study titled "Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF". The purpose of this study is to examine small vessel disease (a condition in which the small arteries in the heart become narrowed). The investigators want to know how the small vessel disease contributes to pre-HFpEF (a condition with inadequate heart muscle function in the setting of preserved mus...
What is the current status of trial NCT03876223?
This trial is currently recruiting. The enrollment target is 180 participants. The study started on 2019-07-24. Estimated completion is 2026-02-28.
What conditions does trial NCT03876223 study?
This clinical trial studies the following conditions: Heart Failure With Preserved Ejection Fraction (HFPEF), Coronary Microvascular Dysfunction.
Who is sponsoring clinical trial NCT03876223?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03876223 being conducted?
This trial has 2 study locations across California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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