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NCT06792552 · ClinicalTrials.gov registry record · Phase 1
A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors
A Phase 1 study of Advanced Solid Tumors, sponsored by NextCure.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 414
- Enrollment target
- 17
- Study locations
NCT06792552 is a Phase 1 study of Advanced Solid Tumors that is actively recruiting participants, run by NextCure. The registered enrollment target is 414 participants, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (111% higher). The trial reports 17 study locations across 14 states.
The verdict
NCT06792552, a Phase 1 study of Advanced Solid Tumors, is actively recruiting participants, sponsored by NextCure.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 414 participants
- Enrollment target
- 17
- Study locations
Study Summary
This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants with Advanced Solid Tumors
Conditions Studied
Interventions
- DRUG SIM0505 for injection
Study Locations (17)
New York
- Roswell Park Cancer Institute - Buffalo
- Icahn School of Medicine at Mount Sinai - New York
China
- Liaoning Cancer Hospital & Institute - Shenyang
- The Fourth Hospital of Hebei Medical University (Heibei Tumor Hospital) - Shijiazhuang
Shandong
- Cancer Hospital of Shandong First Medical University - Jinan
- Affiliated Hospital of Jining Medical University - Jining
Florida
- Sarah Cannon Research Institute (SCRI) - Lake Nona - Orlando
Georgia
- Emory Winship Cancer Institute - Atlanta
Louisiana
- University Medical Center of New Orleans LSU-LCMC Health Cancer Center - New Orleans
Massachusetts
- Dana-Farber Cancer Institute - Boston
New Jersey
- Hackensack University Medical Center - Hackensack
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 414 participants |
| Start Date | 2025-02-26 |
| Est. Completion | 2028-08 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06792552
The ClinicalTrials.gov registry entry for NCT06792552 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 414 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (111% higher). The listed sponsor is NextCure, which has 7 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which SIM0505 for injection is the first listed.
NCT06792552 reports 17 study locations spanning 14 distinct geographic areas - top geographies include New York, China, Shandong.
Frequently Asked Questions
What is clinical trial NCT06792552 about?
NCT06792552 is a clinical study titled "A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors". This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants with Advanced Solid Tumors
What is the current status of trial NCT06792552?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 414 participants. The study started on 2025-02-26. Estimated completion is 2028-08.
What conditions does trial NCT06792552 study?
This clinical trial studies the following conditions: Advanced Solid Tumors.
What interventions are being tested in trial NCT06792552?
The interventions under investigation include: SIM0505 for injection (DRUG).
Who is sponsoring clinical trial NCT06792552?
This trial is sponsored by NextCure, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06792552 being conducted?
This trial has 17 study locations across Florida, Georgia, Louisiana, Massachusetts, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.