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NCT06745479 · ClinicalTrials.gov registry record · NA
Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study
A NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT06745479: Recruiting NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Rutgers, The State University of New Jersey.
NCT06745479 is a NA study of Schizophrenia and Schizoaffective Disorder that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 74 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06745479, a NA study of Schizophrenia and Schizoaffective Disorder, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if attention and ways of thinking impact decision-making and brain processes related to decision-making in people with schizophrenia or schizoaffective disorder relative to people without either condition. It will also learn how brain functioning during decision-making relates to real-world decisions made during daily life. The main questions it aims to answer are: * Does paying attention to specific information impact decision-making and brain processes? * Does thinking in a certain way according to specific 'thinking strategies' improve brain processes related to decision-making? * Does brain functioning during decision-making relate to real-world choices to engage in activities? Researchers will compare brain functioning and decision-making on computer tasks of gambling after participants have been trained to use a positive thinking strategy. They will compare what is different in the brain and behavior when participants use this strategy and when they do not. Participants will also answer brief surveys about activities and feelings for a week in their daily lives. Participants will: * Complete several hours of clinical interviewing, cognitive tests, and surveys of about symptoms, experiences, and personality * Complete computer tasks about gambling decisions during MRI brain scanning and while having their visual attention measured using eye-tracking * Complete brief surveys about their activities and feelings 5 times a day for 1 week using a cell phone. Each survey only take several minutes.
Primary Outcome
Brain activation in the nucleus accumbens (ventral striatum) measured via functional magnetic resonance imaging (fMRI) on trials that are preceded by the cognitive regulation strategy relative to trials without the cognitive regulation strategy.
Conditions Studied
Interventions
- BEHAVIORAL Positive Emotion Upregulation
Study Locations (1)
New Jersey
- Center for Advanced Human Brain Imaging Research - Piscataway
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2025-01-07 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT06745479 shows while recruiting
NCT06745479 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (66% lower).
The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 1 intervention - of which Positive Emotion Upregulation is the first listed.
NCT06745479 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT06745479 about?
NCT06745479 is a clinical study titled "Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study". The goal of this clinical trial is to learn if attention and ways of thinking impact decision-making and brain processes related to decision-making in people with schizophrenia or schizoaffective disorder relative to people without either condition. It will also learn how brain functioning during de...
What is the current status of trial NCT06745479?
This trial is currently recruiting. It is a NA study. The enrollment target is 74 participants. The study started on 2025-01-07. Estimated completion is 2027-06-30.
What conditions does trial NCT06745479 study?
This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder, Control Subjects.
What interventions are being tested in trial NCT06745479?
The interventions under investigation include: Positive Emotion Upregulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06745479?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06745479 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06745479's enrollment target sits among peer trials
74 173rd of 315 higher than 143 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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