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NCT06693648 · ClinicalTrials.gov registry record · Phase 3
A Study to Evaluate Efficacy and Safety of AMZ001 for the Treatment of Knee Osteoarthritis Symptoms
A Phase 3 study of Osteoarthritis, Knee and Osteoarthritis of Knee, sponsored by Amzell.
- Active
- Registry status
- Phase 3
- Development phase
- 540
- Enrollment target
- 11
- Study locations
NCT06693648 is a Phase 3 study of Osteoarthritis, Knee and Osteoarthritis of Knee that is active but no longer recruiting, run by Amzell. The registered enrollment target is 540 participants, roughly in line with the 574-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target. The trial reports 11 study locations across 7 states.
The verdict
NCT06693648, a Phase 3 study of Osteoarthritis, Knee and Osteoarthritis of Knee, is active but no longer recruiting, sponsored by Amzell.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 540 participants
- Enrollment target
- 11
- Study locations
Study Summary
This is a multicenter, randomized, double-blind, placebo-controlled, parallel group, 6-week trial of a formulation of AMZ001 once daily versus placebo once daily.
Conditions Studied
Interventions
- DRUG Placebo gel
- DRUG AMZ001 Diclofenac gel
Study Locations (11)
Other
- hong Kong Center for Clinical Research - Hong Kong
- Charles University - Prague
- Sanos Clinic - Herlev
- Medyczne Centrum Hetmanska Piotr Leszczynski - Poznan
Florida
- Eastern Research Inc - Hialeah
- Future Medical Research - Longwood
California
- Millennium Clinical Trials - Thousand Oaks
Louisiana
- DelRicht Research - New Orleans
Maryland
- DelRicht Research - Rockville
Michigan
- Oakland Medical Research - Troy
North Carolina
- West Clinical Research - Morehead City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 540 participants |
| Start Date | 2025-02-18 |
| Est. Completion | 2026-04 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06693648
The ClinicalTrials.gov registry entry for NCT06693648 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 540 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 574-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target. The listed sponsor is Amzell, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions - of which Placebo gel is the first listed.
NCT06693648 reports 11 study locations spanning 7 distinct geographic areas - top geographies include Other, Florida, California.
Frequently Asked Questions
What is clinical trial NCT06693648 about?
NCT06693648 is a clinical study titled "A Study to Evaluate Efficacy and Safety of AMZ001 for the Treatment of Knee Osteoarthritis Symptoms". This is a multicenter, randomized, double-blind, placebo-controlled, parallel group, 6-week trial of a formulation of AMZ001 once daily versus placebo once daily.
What is the current status of trial NCT06693648?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 540 participants. The study started on 2025-02-18. Estimated completion is 2026-04.
What conditions does trial NCT06693648 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Osteoarthritis of Knee.
What interventions are being tested in trial NCT06693648?
The interventions under investigation include: Placebo gel (DRUG), AMZ001 Diclofenac gel (DRUG).
Who is sponsoring clinical trial NCT06693648?
This trial is sponsored by Amzell, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06693648 being conducted?
This trial has 11 study locations across California, Florida, Louisiana, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.