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A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure
NCT06692764 · View on ClinicalTrials.gov ↗
Study Summary
This is a Phase II, multi-centre, randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of AZD0780 Dose 1 versus placebo on systolic blood pressure (SBP) at Week 4, as measured by 24-hour ambulatory blood pressure monitoring (ABPM) in participants with ASCVD or risk equivalents and LDL-C ≥ 70 mg/dL, on stable medication.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG AZD0780
Study Locations (20)
Florida
- Research Site — Boca Raton
- Research Site — Hialeah
- Research Site — Jacksonville
- Research Site — Miami
- Research Site — Miami
- Research Site — Miami
- Research Site — Miami
- Research Site — Ocala
- Research Site — Port Orange
- Research Site — Tamarac
California
- Research Site — Inglewood
- Research Site — Northridge
- Research Site — Pomona
Illinois
- Research Site — Chicago
Maryland
- Research Site — Potomac
Massachusetts
- Research Site — New Bedford
New York
- Research Site — New Windsor
Ohio
- Research Site — Beavercreek
Pennsylvania
- Research Site — Horsham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 202 participants |
| Start Date | 2024-10-30 |
| Est. Completion | 2025-05-02 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06692764
The ClinicalTrials.gov registry entry for NCT06692764 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 202 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Atherosclerotic Cardiovascular Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06692764 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06692764 about?
NCT06692764 is a clinical study titled "A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure". This is a Phase II, multi-centre, randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of AZD0780 Dose 1 versus placebo on systolic blood pressure (SBP) at Week 4, as measured by 24-hour ambulatory blood pressure monitoring (ABPM) in participants with ASCVD or risk eq...
What is the current status of trial NCT06692764?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 202 participants. The study started on 2024-10-30. Estimated completion is 2025-05-02.
What conditions does trial NCT06692764 study?
This clinical trial studies the following conditions: Atherosclerotic Cardiovascular Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06692764?
The interventions under investigation include: Placebo (DRUG), AZD0780 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06692764?
This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06692764 being conducted?
This trial has 20 study locations across California, Florida, Illinois, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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