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NCT06688539 · ClinicalTrials.gov registry record · Phase 4
E-cigarette Cessation in Adults Who Co-use Cannabis
A Phase 4 study of Tobacco Use Disorder and Nicotine Dependence, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 105
- Enrollment target
- 3
- Study locations
NCT06688539 is a Phase 4 study of Tobacco Use Disorder and Nicotine Dependence that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 105 participants, below the 238-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (56% lower). The trial reports 3 study locations across 1 state.
The verdict
NCT06688539, a Phase 4 study of Tobacco Use Disorder and Nicotine Dependence, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 105 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to better understand tobacco outcomes using a commonly prescribed stop smoking medication (varenicline) and financial incentives for adults who also use cannabis. Varenicline is not FDA approved for e-cigarette cessation, but is FDA approved for cigarette cessation. Investigators are also interested in how cannabis/marijuana and tobacco interact during a tobacco quit attempt. All participants will receive e-cigarette cessation treatment for 12 weeks. To qualify, participants must be between the ages of 18-40 and use both e-cigarettes and cannabis. Participants do not need to be interested in quitting cannabis to qualify. This study is being conducted at three sites: the Medical University of South Carolina in Charleston, SC, Behavioral Health Services in Pickens, SC, and MUSC Lancaster in Lancaster, SC.
Conditions Studied
Interventions
- BEHAVIORAL Counseling
- DRUG Varenicline Pill
- BEHAVIORAL Contingency management
Study Locations (3)
South Carolina
- MUSC Charleston - Charleston
- MUSC Lancaster - Lancaster
- Behavioral Health Services of Pickens County - Pickens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2025-02-19 |
| Est. Completion | 2026-09-01 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06688539
The ClinicalTrials.gov registry entry for NCT06688539 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 238-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (56% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Tobacco Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which Counseling is the first listed.
NCT06688539 reports 3 study locations spanning 1 distinct geographic area - top geographies include South Carolina.
Frequently Asked Questions
What is clinical trial NCT06688539 about?
NCT06688539 is a clinical study titled "E-cigarette Cessation in Adults Who Co-use Cannabis". The purpose of this study is to better understand tobacco outcomes using a commonly prescribed stop smoking medication (varenicline) and financial incentives for adults who also use cannabis. Varenicline is not FDA approved for e-cigarette cessation, but is FDA approved for cigarette cessation. Inve...
What is the current status of trial NCT06688539?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 105 participants. The study started on 2025-02-19. Estimated completion is 2026-09-01.
What conditions does trial NCT06688539 study?
This clinical trial studies the following conditions: Tobacco Use Disorder, Nicotine Dependence.
What interventions are being tested in trial NCT06688539?
The interventions under investigation include: Counseling (BEHAVIORAL), Varenicline Pill (DRUG), Contingency management (BEHAVIORAL).
Who is sponsoring clinical trial NCT06688539?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06688539 being conducted?
This trial has 3 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.