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NCT05587361 · ClinicalTrials.gov registry record · Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

A Phase 4 study of Tobacco Use Disorder and Nicotine Dependence, sponsored by University of Oklahoma.

Recruiting
Registry status
Phase 4
Development phase
80
Enrollment target
1
Study location

NCT05587361 is a Phase 4 study of Tobacco Use Disorder and Nicotine Dependence that is actively recruiting participants, run by University of Oklahoma. The registered enrollment target is 80 participants, below the 238-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05587361, a Phase 4 study of Tobacco Use Disorder and Nicotine Dependence, is actively recruiting participants, sponsored by University of Oklahoma.

RECRUITING
Registry status
Phase 4
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This study is designed to investigate the effects of a beta-adrenergic antagonist (Propranolol; 40 mg IR) and nicotine patch (14 mg) administered alone and in combination on neurobiological and behavioral responses to smoking cues in ongoing cigarette smokers. This is a basic experimental study in humans and participants will not take these medications for an extended period or make a cessation attempt as part of their involvement in this research project.

Conditions Studied

Tobacco Use Disorder Nicotine Dependence Cigarette Smoking

Interventions

  • DRUG Propranolol
  • DRUG Nicotine Patch
  • DRUG Placebo Propranolol
  • DRUG Placebo Patch

Study Locations (1)

Oklahoma

  • Hardesty Center for Clinical Research and Neuroscience - Tulsa

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-11-26
Est. Completion 2026-03-01
Phase Phase 4

Sponsor

University of Oklahoma

358 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05587361

The ClinicalTrials.gov registry entry for NCT05587361 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 238-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (66% lower). The listed sponsor is University of Oklahoma, which has 358 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Tobacco Use Disorder appearing as the primary indexed condition, and to 4 interventions - of which Propranolol is the first listed.

NCT05587361 reports 1 study location spanning 1 distinct geographic area - top geographies include Oklahoma.

Frequently Asked Questions

What is clinical trial NCT05587361 about?

NCT05587361 is a clinical study titled "Beta-Adrenergic Modulation of Drug Cue Reactivity". This study is designed to investigate the effects of a beta-adrenergic antagonist (Propranolol; 40 mg IR) and nicotine patch (14 mg) administered alone and in combination on neurobiological and behavioral responses to smoking cues in ongoing cigarette smokers. This is a basic experimental study in h...

What is the current status of trial NCT05587361?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2024-11-26. Estimated completion is 2026-03-01.

What conditions does trial NCT05587361 study?

This clinical trial studies the following conditions: Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking.

What interventions are being tested in trial NCT05587361?

The interventions under investigation include: Propranolol (DRUG), Nicotine Patch (DRUG), Placebo Propranolol (DRUG), Placebo Patch (DRUG).

Who is sponsoring clinical trial NCT05587361?

This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05587361 being conducted?

This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.