Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02803957 · ClinicalTrials.gov registry record · NA

Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair

A NA study of Mitral Valve Insufficiency, sponsored by NeoChord.

Recruiting
Registry status
NA
Development phase
585
Enrollment target
18
Study locations

NCT02803957: Recruiting NA study of Mitral Valve Insufficiency, sponsored by NeoChord.

NCT02803957 is a NA study of Mitral Valve Insufficiency that is actively recruiting participants, run by NeoChord. The registered enrollment target is 585 participants, above the 333-participant average among 11 other Mitral Valve Insufficiency trials with a reported enrollment target (76% higher). The trial reports 18 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02803957, a NA study of Mitral Valve Insufficiency, is actively recruiting participants, sponsored by NeoChord.

RECRUITING
Registry status
NA
Development phase
585 participants
Enrollment target
18
Study locations

Study Summary

The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).

Conditions Studied

Interventions

  • DEVICE NeoChord DS1000
  • DEVICE Surgical Mitral Valve Repair

Study Locations (18)

California

  • Sutter Health/Alta Bates Summitt Medical Center - Oakland
  • Mercy General Hospital - Sacramento
  • Stanford University - Stanford

Pennsylvania

  • Pinnacle Health - Harrisburg
  • Penn State Milton S. Hershey Medical Center - Hershey
  • University of Pittsburgh Medical Center - Pittsburgh

New York

  • Mount Sinai, Icahn School of Medicine - New York
  • Columbia University Medical Center - New York

District of Columbia

  • MedStar Washington Hospital Center - Washington D.C.

Florida

  • Florida Hospital - Orlando

Georgia

  • Piedmont Heart Institute - Atlanta

Indiana

  • Franciscan Health - Indianapolis

Maryland

  • Johns Hopkins University - Baltimore

Trial Details

FieldValue
Enrollment Target 585 participants
Start Date 2016-11-03
Est. Completion 2027-07
Phase NA
NeoChord

1 total trials

What NCT02803957 shows while recruiting

NCT02803957 is an interventional study that assigns participants to a tested intervention. The registered 585 participants enrollment target is mid-sized for trials with a published cap, above the 333-participant average among 11 other Mitral Valve Insufficiency trials with a reported enrollment target (76% higher).

The record links to 1 condition, with Mitral Valve Insufficiency appearing as the primary indexed condition, and to 2 interventions - of which NeoChord DS1000 is the first listed.

NCT02803957 lists 18 locations in 13 states (California, Pennsylvania, New York).

Frequently Asked Questions

What is clinical trial NCT02803957 about?

NCT02803957 is a clinical study titled "Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair". The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgica...

What is the current status of trial NCT02803957?

This trial is currently recruiting. It is a NA study. The enrollment target is 585 participants. The study started on 2016-11-03. Estimated completion is 2027-07.

What conditions does trial NCT02803957 study?

This clinical trial studies the following conditions: Mitral Valve Insufficiency.

What interventions are being tested in trial NCT02803957?

The interventions under investigation include: NeoChord DS1000 (DEVICE), Surgical Mitral Valve Repair (DEVICE).

Who is sponsoring clinical trial NCT02803957?

This trial is sponsored by NeoChord, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02803957 being conducted?

This trial has 18 study locations across California, District of Columbia, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Mitral Valve Insufficiency

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02803957's enrollment target sits among peer trials

585 3rd of 11 higher than 9 of 11 other Mitral Valve Insufficiency trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Mitral Valve Insufficiency trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06680869 · 585 participants · Phase 3

    Early Amiodarone in Shockable Cardiac Arrest

  • NCT04134260 · 586 participants · Phase 3

    Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

  • NCT06100770 · 586 participants

    Aveir AR Coverage With Evidence Development (CED) Study

  • NCT06183281 · 586 participants · NA

    Integrating Nonpharmacologic Strategies for Pain With Inclusion, Respect, and Equity

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02803957, the US trial registry maintained by the National Library of Medicine. NCT02803957 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.