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NCT06670521 · ClinicalTrials.gov registry record · Phase 2

Corticosteroids for Post-Extubation Dysphagia

A Phase 2 study of Dysphagia and Laryngeal Edema, sponsored by University of Colorado, Denver.

Recruiting
Registry status
Phase 2
Development phase
80
Enrollment target
1
Study location

NCT06670521 is a Phase 2 study of Dysphagia and Laryngeal Edema that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 80 participants, below the 170-participant average among 35 other Dysphagia trials with a reported enrollment target (53% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06670521, a Phase 2 study of Dysphagia and Laryngeal Edema, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
Phase 2
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This is a placebo-controlled, double-blind randomized trial of a short course of intravenous corticosteroids for Acute Respiratory Failure Survivors with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) documented laryngeal edema. Study was leveraged using the existing R01 grant infrastructure COMIRB # 21-3873, study design, and research methods. Patients for the study proposed will have already been enrolled in the R01 longitudinal cohort study. The sites to perform this study include Colorado, BU, Yale, and Stanford. Those R01-enrolled patients with laryngeal edema on their initial FEES examination: defined as the revised Patterson edema score greater than zero, will be approached for enrollment.

Interventions

  • DRUG Methylprednisolone
  • DRUG Normal Saline

Study Locations (1)

Colorado

  • University of Colorado - Aurora

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-11-13
Est. Completion 2027-05-31
Phase Phase 2

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT06670521

The ClinicalTrials.gov registry entry for NCT06670521 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 170-participant average among 35 other Dysphagia trials with a reported enrollment target (53% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Dysphagia appearing as the primary indexed condition, and to 2 interventions - of which Methylprednisolone is the first listed.

NCT06670521 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT06670521 about?

NCT06670521 is a clinical study titled "Corticosteroids for Post-Extubation Dysphagia". This is a placebo-controlled, double-blind randomized trial of a short course of intravenous corticosteroids for Acute Respiratory Failure Survivors with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) documented laryngeal edema. Study was leveraged using the existing R01 grant infrastructure ...

What is the current status of trial NCT06670521?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2024-11-13. Estimated completion is 2027-05-31.

What conditions does trial NCT06670521 study?

This clinical trial studies the following conditions: Dysphagia, Laryngeal Edema.

What interventions are being tested in trial NCT06670521?

The interventions under investigation include: Methylprednisolone (DRUG), Normal Saline (DRUG).

Who is sponsoring clinical trial NCT06670521?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06670521 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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