Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)
NCT06598306 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to evaluate the safety and tolerability of subcutaneous (SC) tarlatamab.
Conditions Studied
Interventions
- DRUG Tarlatamab
Study Locations (20)
Other
- Universitair Ziekenhuis Gent — Ghent
- Universitair Ziekenhuis Leuven - Campus Gasthuisberg — Leuven
- Centre Hospitalier Universitaire de Liege - Sart Tilman — Liège
- Universitaetsklinikum Regensburg — Regensburg
- Universitaetsklinikum Wuerzburg — Würzburg
- Wakayama Medical University Hospital — Wakayama
- Uniwersyteckie Centrum Kliniczne — Gdansk
- Instytut Centrum Zdrowia Matki Polki — Lodz
- Wojewodzki Szpital im Sw Ojca Pio w Przemyslu — Przemyśl
New South Wales
- Chris OBrien Lifehouse — Camperdown
- Calvary Mater Newcastle Hospital — Waratah
California
- University of Southern California, Norris Comprehensive Cancer Center — Los Angeles
Illinois
- University of Illinois Chicago — Chicago
Michigan
- Trinity Health Saint Joseph Mercy Ann Arbor — Ann Arbor
South Dakota
- Avera Cancer Institute — Sioux Falls
Texas
- University of Texas MD Anderson Cancer Center — Houston
Washington
- Swedish Cancer Institute — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2024-10-07 |
| Est. Completion | 2030-03-27 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06598306
The ClinicalTrials.gov registry entry for NCT06598306 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 220 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Extensive Stage Small Cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention — of which Tarlatamab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06598306 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Other, New South Wales, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06598306 about?
NCT06598306 is a clinical study titled "Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)". The primary objective of this study is to evaluate the safety and tolerability of subcutaneous (SC) tarlatamab.
What is the current status of trial NCT06598306?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 220 participants. The study started on 2024-10-07. Estimated completion is 2030-03-27.
What conditions does trial NCT06598306 study?
This clinical trial studies the following conditions: Extensive Stage Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06598306?
The interventions under investigation include: Tarlatamab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06598306?
This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06598306 being conducted?
This trial has 20 study locations across California, Illinois, Michigan, South Dakota, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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