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ClinicalTrials.gov 12 recruiting now full pipeline small index

Genetic Predisposition: full-pipeline trial registry

12 of 15 indexed Genetic Predisposition trials are currently recruiting.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 12 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Genetic Predisposition: 15 US clinical trials tracked, 12 recruiting.

Genetic Predisposition is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Dana-Farber Cancer Institute, running 2 of these trials.

Enrollment posture brief

Registry condition genetic-predisposition

OPEN 12 | RECR 80% | LATE 1 | EARLY 1 | RANK #1140 | SPON 2

Nearest open-share peer: Ablation (80% recruiting · 5 trials)

Genetic Predisposition (this)80%Advanced Lung Non-Small Cell53.3%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Genetic Predisposition

Genetic Predisposition lists 12 open slots (80% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Genetic Predisposition on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Genetic Predisposition is recruiting above its size-band peers.

    12 of 15 indexed trials (80%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Genetic Predisposition trials is spread across many organizations.

    Dana-Farber Cancer Institute accounts for 2 of 15 trials (13.3%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Genetic Predisposition enrolment sits around 400 participants.

    Median target enrolment is 400 among the 15 trials that report a genuine target (sentinel values excluded). 4 of those (26.7%) plan for fewer than 100 participants.

  4. Genetic Predisposition splits between interventional and observational designs.

    8 interventional and 7 observational studies make up this index (53.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 41

Open and recent trials

15 total, page 1 of 1

RECRUITING 20,000 participants

Pancreatic Cancer Early Detection Consortium

Arbor Research Collaborative for Health

NCT04970056

RECRUITING 4,900 participants

InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort

Columbia University

NCT05929976

RECRUITING 1,000 participants

Vascular Disease Discovery Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT03538639

RECRUITING NA 1,000 participants

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

University of Pennsylvania

NCT06377033

RECRUITING 600 participants

APOL1 Genetic Testing in African Americans

St. Louis University

NCT05656261

RECRUITING 500 participants

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

Dana-Farber Cancer Institute

NCT05587439

RECRUITING 200 participants

Prostate Tissue BioBank

Abramson Cancer Center at Penn Medicine

NCT06659614

RECRUITING Phase 4 125 participants

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Massachusetts General Hospital

NCT06003153

RECRUITING 125 participants

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

St. Jude Children's Research Hospital

NCT05849155

RECRUITING NA 96 participants

Genetic Information Assistant in Telegenetics

University of Virginia

NCT06089421

RECRUITING Phase 1 40 participants

Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

Children's Mercy Hospital Kansas City

NCT06554288

RECRUITING NA 40 participants

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Dana-Farber Cancer Institute

NCT05759143

ACTIVE NOT RECRUITING NA 400 participants

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

Abramson Cancer Center at Penn Medicine

NCT04774445

ACTIVE NOT RECRUITING NA 70 participants

Overcoming Barriers to Accessing Genetic Medicine

Boston Children's Hospital

NCT05064241

COMPLETED NA 20,184 participants

Early Detection of GEnetic Risk (EDGE)

University of Washington

NCT04746794

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 4 1

Named interventions

Most-linked intervention names on Genetic Predisposition records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Population-level screening Behavioral
1 trials
Access to Genetic Counselor for answering questions Other
1 trials
MyCancerGene Behavioral
1 trials
Telegenetics with UVA genetic counselor Other
1 trials
Genetic Information Assistant Other
1 trials
Assessment of the frequency of APOL-1 renal risk variant in the black population, and evaluating their attitudes about genetic testing and APOL1 genotype via self-administered surveys Genetic
1 trials
Nest Platform Behavioral
1 trials
Behavioral nudge Behavioral
1 trials

US sites by state

Facility locations filed on Genetic Predisposition trials. A trial with sites in several states counts in each.

Massachusetts 4 trials
Pennsylvania 3 trials
Missouri 2 trials
Washington 1 trials
Virginia 1 trials
Tennessee 1 trials
New York 1 trials
Montana 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Genetic Predisposition page

15 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Genetic Predisposition condition card totals 15 registered trials; most-linked intervention Population-level screening; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.