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ClinicalTrials.gov 12 recruiting now official registry

Genetic Predisposition clinical trials

12 of 15 indexed Genetic Predisposition trials are currently recruiting.

15 US clinical trials · 12 currently recruiting

Genetic Predisposition is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Dana-Farber Cancer Institute, running 2 of these trials.

The research picture

Genetic Predisposition has 15 registered US clinical trials, 12 of them open to new participants right now, about 80% of the total.

12
recruiting participants now
80%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Dana-Farber Cancer Institute
Phase 11Phase 41

Active & Recent Trials

15 total, page 1 of 1

RECRUITING 20,000 participants

Pancreatic Cancer Early Detection Consortium

Arbor Research Collaborative for Health

NCT04970056

RECRUITING 4,900 participants

InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort

Columbia University

NCT05929976

RECRUITING 1,000 participants

Vascular Disease Discovery Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT03538639

RECRUITING NA 1,000 participants

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

University of Pennsylvania

NCT06377033

RECRUITING 600 participants

APOL1 Genetic Testing in African Americans

St. Louis University

NCT05656261

RECRUITING 500 participants

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

Dana-Farber Cancer Institute

NCT05587439

RECRUITING 200 participants

Prostate Tissue BioBank

Abramson Cancer Center at Penn Medicine

NCT06659614

RECRUITING Phase 4 125 participants

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Massachusetts General Hospital

NCT06003153

RECRUITING 125 participants

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

St. Jude Children's Research Hospital

NCT05849155

RECRUITING NA 96 participants

Genetic Information Assistant in Telegenetics

University of Virginia

NCT06089421

RECRUITING Phase 1 40 participants

Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

Children's Mercy Hospital Kansas City

NCT06554288

RECRUITING NA 40 participants

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Dana-Farber Cancer Institute

NCT05759143

ACTIVE NOT RECRUITING NA 400 participants

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

Abramson Cancer Center at Penn Medicine

NCT04774445

ACTIVE NOT RECRUITING NA 70 participants

Overcoming Barriers to Accessing Genetic Medicine

Boston Children's Hospital

NCT05064241

COMPLETED NA 20,184 participants

Early Detection of GEnetic Risk (EDGE)

University of Washington

NCT04746794

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Genetic Predisposition Trial Landscape

15 indexed Genetic Predisposition studies · 12 recruiting (80%).

Phase mix: 1 late (III/IV) vs 1 early (I/II).

Top sponsor: Dana-Farber Cancer Institute (2 trials), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Genetic Predisposition?

PlainTrial tracks 15 US clinical trials for Genetic Predisposition, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Genetic Predisposition?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.