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NCT05547698 · ClinicalTrials.gov registry record · NA
A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation
A NA study of Lung Transplant, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 228
- Enrollment target
- 5
- Study locations
NCT05547698: Recruiting NA study of Lung Transplant, sponsored by Mayo Clinic.
NCT05547698 is a NA study of Lung Transplant that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 228 participants, below the 1,261-participant average among 15 other Lung Transplant trials with a reported enrollment target (82% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05547698, a NA study of Lung Transplant, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 228 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this research study is to compare the technique of performing bilateral lung transplantation off-pump vs venoarterial ECMO (VA ECMO). The goal of the trial is to determine which technique has lower rates of primary graft dysfunction.
Primary Outcome
Rate of PGD according to the The International Society for Heart and Lung Transplantation (ISHLT) classification
Conditions Studied
Interventions
- PROCEDURE Off-pump lung transplantation
- PROCEDURE Venoarterial ECMO lung transplantation
Study Locations (5)
Pennsylvania
- University of Pennsylvania - Philadelphia
- Temple University Hospital - Philadelphia
Kentucky
- University Of Louisville - Louisville
Minnesota
- Mayo Clinic Rochester - Rochester
Texas
- Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 228 participants |
| Start Date | 2022-09-17 |
| Est. Completion | 2027-09 |
| Phase | NA |
What NCT05547698 shows while recruiting
NCT05547698 is an interventional study that assigns participants to a tested intervention. The registered 228 participants enrollment target is mid-sized for trials with a published cap, below the 1,261-participant average among 15 other Lung Transplant trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Lung Transplant appearing as the primary indexed condition, and to 2 interventions - of which Off-pump lung transplantation is the first listed.
NCT05547698 lists 5 locations in 4 states (Pennsylvania, Kentucky, Minnesota).
Frequently Asked Questions
What is clinical trial NCT05547698 about?
NCT05547698 is a clinical study titled "A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation". The purpose of this research study is to compare the technique of performing bilateral lung transplantation off-pump vs venoarterial ECMO (VA ECMO). The goal of the trial is to determine which technique has lower rates of primary graft dysfunction.
What is the current status of trial NCT05547698?
This trial is currently recruiting. It is a NA study. The enrollment target is 228 participants. The study started on 2022-09-17. Estimated completion is 2027-09.
What conditions does trial NCT05547698 study?
This clinical trial studies the following conditions: Lung Transplant.
What interventions are being tested in trial NCT05547698?
The interventions under investigation include: Off-pump lung transplantation (PROCEDURE), Venoarterial ECMO lung transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT05547698?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05547698 being conducted?
This trial has 5 study locations across Kentucky, Minnesota, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Transplant
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05547698's enrollment target sits among peer trials
228 8th of 15 higher than 8 of 15 other Lung Transplant trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Transplant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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