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NCT06471647 · ClinicalTrials.gov registry record · Early Phase 1

Effects of Drugs on Stress Memories

A Early Phase 1 study, sponsored by University of Chicago.

Completed
Registry status
Early Phase 1
Development phase
36
Enrollment target

NCT06471647: Completed Early Phase 1 study, sponsored by University of Chicago.

NCT06471647 is a Early Phase 1 study that has completed, run by University of Chicago. The registered enrollment target is 36 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06471647, a Early Phase 1 study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Early Phase 1
Development phase
36 participants
Enrollment target

Study Summary

There is evidence that cannabinoids, including delta-9-tetrahydrocannabinol (THC), reduce responses to acute stress and fear-related stimuli, but few studies have examined the effects of THC on memories of stressful experiences. The researchers hypothesize that THC will attenuate behavioral and physiological responses to negative valence stimuli, including memories of aversive experiences.

Primary Outcome

Using a visual analog scale participants will rate feelings of 'distress' 'arousal' and 'valence'. Scores range from 0-100 with higher scores indicating greater responses on particular items

Interventions

  • DRUG Placebo
  • DRUG delta-9-tetrahydrocannabinol (THC) (5)
  • DRUG delta-9-tetrahydrocannabinol (THC) (10)

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2024-07-01
Est. Completion 2025-03-25
Phase Early Phase 1
University of Chicago

796 total trials

What the finished NCT06471647 record still lists

NCT06471647 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT06471647 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06471647 about?

NCT06471647 is a clinical study titled "Effects of Drugs on Stress Memories". There is evidence that cannabinoids, including delta-9-tetrahydrocannabinol (THC), reduce responses to acute stress and fear-related stimuli, but few studies have examined the effects of THC on memories of stressful experiences. The researchers hypothesize that THC will attenuate behavioral and phys...

What is the current status of trial NCT06471647?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 36 participants. The study started on 2024-07-01. Estimated completion is 2025-03-25.

What interventions are being tested in trial NCT06471647?

The interventions under investigation include: Placebo (DRUG), delta-9-tetrahydrocannabinol (THC) (5) (DRUG), delta-9-tetrahydrocannabinol (THC) (10) (DRUG).

Who is sponsoring clinical trial NCT06471647?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06471647's enrollment target sits among peer trials

36 712th of 2000 higher than 1,266 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06471647, the US trial registry maintained by the National Library of Medicine. NCT06471647 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.