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NCT06456268 · ClinicalTrials.gov registry record · NA
VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)
A NA study of Pain, Postoperative and Opioid Use, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06456268: Recruiting NA study of Pain, Postoperative and Opioid Use, sponsored by Columbia University.
NCT06456268 is a NA study of Pain, Postoperative and Opioid Use that is actively recruiting participants, run by Columbia University. The registered enrollment target is 130 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06456268, a NA study of Pain, Postoperative and Opioid Use, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this project is to test the effects of the VibraCool mechanical stimulation neuromodulatory therapeutic device on post-operative pain and opioid use following anterior crucitate ligament reconstruction (ACLR), and thus residual opioids in circulation.
Primary Outcome
Scale of 0 to 10, with 10 being the worst pain and 0 being no pain. Will record daily mean VAS pain scores over the first seven post-operative days
Conditions Studied
Interventions
- DEVICE VibraCool mechanical stimulation and neuromodulatory therapeutic device
- DEVICE Cryocompression (Game Ready, Bregs) device
- DEVICE Standard ice packs
Study Locations (1)
New York
- Columbia University Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2026-06 |
| Est. Completion | 2026-11-30 |
| Phase | NA |
What NCT06456268 shows while recruiting
NCT06456268 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (52% lower).
The record links to 5 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 3 interventions - of which VibraCool mechanical stimulation and neuromodulatory therapeutic device is the first listed.
NCT06456268 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06456268 about?
NCT06456268 is a clinical study titled "VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)". The goal of this project is to test the effects of the VibraCool mechanical stimulation neuromodulatory therapeutic device on post-operative pain and opioid use following anterior crucitate ligament reconstruction (ACLR), and thus residual opioids in circulation.
What is the current status of trial NCT06456268?
This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2026-06. Estimated completion is 2026-11-30.
What conditions does trial NCT06456268 study?
This clinical trial studies the following conditions: Pain, Postoperative, Opioid Use, ACL, Cryotherapy Effect, Vibration; Exposure.
What interventions are being tested in trial NCT06456268?
The interventions under investigation include: VibraCool mechanical stimulation and neuromodulatory therapeutic device (DEVICE), Cryocompression (Game Ready, Bregs) device (DEVICE), Standard ice packs (DEVICE).
Who is sponsoring clinical trial NCT06456268?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06456268 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06456268's enrollment target sits among peer trials
130 33rd of 113 higher than 81 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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