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NCT06436846 · ClinicalTrials.gov registry record
Genomic Risk in Retroperitoneal Sarcoma
A clinical trial of Soft Tissue Sarcoma and Retroperitoneal Liposarcoma, sponsored by Fox Chase Cancer Center.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT06436846: Recruiting study of Soft Tissue Sarcoma and Retroperitoneal Liposarcoma, sponsored by Fox Chase Cancer Center.
NCT06436846 is a study of Soft Tissue Sarcoma and Retroperitoneal Liposarcoma that is actively recruiting participants, run by Fox Chase Cancer Center. The registered enrollment target is 50 participants, below the 78-participant average among 55 other Soft Tissue Sarcoma trials with a reported enrollment target (36% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06436846, a study of Soft Tissue Sarcoma and Retroperitoneal Liposarcoma, is actively recruiting participants, sponsored by Fox Chase Cancer Center.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease. Often, tumors recur in locations within the retroperitoneum remote from the original primary tumor. This study hypothesizes that normal appearing retroperitoneal fat actually harbors underlying genetic changes which predispose to development of future liposarcoma. To accomplish this goal, retroperitoneal fat is sampled from quadrants within and remote from the primary tumor and is subsequently subjected to genetic analyses looking for such predisposing factors.
Primary Outcome
MDM2 amplification of primary tumors and fat samples will be tested by immunohistochemistry and/or fluorescence in situ hybridization.
Conditions Studied
Interventions
- OTHER Biospecimen sample collection during standard-of-care surgery
Study Locations (1)
Pennsylvania
- Fox Chase Cancer Center - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-03-07 |
| Est. Completion | 2027-08-01 |
What NCT06436846 shows while recruiting
NCT06436846 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 78-participant average among 55 other Soft Tissue Sarcoma trials with a reported enrollment target (36% lower).
The record links to 2 conditions, with Soft Tissue Sarcoma appearing as the primary indexed condition, and to 1 intervention - of which Biospecimen sample collection during standard-of-care surgery is the first listed.
NCT06436846 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06436846 about?
NCT06436846 is a clinical study titled "Genomic Risk in Retroperitoneal Sarcoma". The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease. Often, tumors recur in locations within the retroperitoneum remote from the original primary tumor. This study hypothesiz...
What is the current status of trial NCT06436846?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2022-03-07. Estimated completion is 2027-08-01.
What conditions does trial NCT06436846 study?
This clinical trial studies the following conditions: Soft Tissue Sarcoma, Retroperitoneal Liposarcoma.
What interventions are being tested in trial NCT06436846?
The interventions under investigation include: Biospecimen sample collection during standard-of-care surgery (OTHER).
Who is sponsoring clinical trial NCT06436846?
This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06436846 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Soft Tissue Sarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06436846's enrollment target sits among peer trials
50 18th of 55 higher than 36 of 55 other Soft Tissue Sarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Soft Tissue Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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