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NCT06424132 · ClinicalTrials.gov registry record · NA

Thermogenic Silencer Regulatory Factors in Humans

A NA study of Obesity and Metabolic Disease, sponsored by Rockefeller University.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT06424132 is a NA study of Obesity and Metabolic Disease that is actively recruiting participants, run by Rockefeller University. The registered enrollment target is 120 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06424132, a NA study of Obesity and Metabolic Disease, is actively recruiting participants, sponsored by Rockefeller University.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

A promising approach to correct the metabolic dysfunction associated with obesity is to activate brown fat non-shivering thermogenesis (NST). A critical limitation with NST as a therapeutic option, however, is that this beneficial process is silenced under human physiological temperature conditions and the mechanisms of how this occurs is unknown. This study will be the first to identify human NST silencing factors that may be targeted for the treatment of obesity and metabolic disorders.

Interventions

  • OTHER Fasting
  • OTHER Cold Vest Exposure Period
  • OTHER Rewarming Exposure Period

Study Locations (1)

New York

  • Rockefeller University - New York

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2024-08-16
Est. Completion 2027-05
Phase NA

Sponsor

Rockefeller University

117 total trials

What the Registry Record Tells You About NCT06424132

The ClinicalTrials.gov registry entry for NCT06424132 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower). The listed sponsor is Rockefeller University, which has 117 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Fasting is the first listed.

NCT06424132 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06424132 about?

NCT06424132 is a clinical study titled "Thermogenic Silencer Regulatory Factors in Humans". A promising approach to correct the metabolic dysfunction associated with obesity is to activate brown fat non-shivering thermogenesis (NST). A critical limitation with NST as a therapeutic option, however, is that this beneficial process is silenced under human physiological temperature conditions ...

What is the current status of trial NCT06424132?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2024-08-16. Estimated completion is 2027-05.

What conditions does trial NCT06424132 study?

This clinical trial studies the following conditions: Obesity, Metabolic Disease, Cold Exposure.

What interventions are being tested in trial NCT06424132?

The interventions under investigation include: Fasting (OTHER), Cold Vest Exposure Period (OTHER), Rewarming Exposure Period (OTHER).

Who is sponsoring clinical trial NCT06424132?

This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06424132 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.