Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cold Exposure: early-phase trial registry
2 of 4 indexed Cold Exposure trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #4,115 of 28,707 conditions by registered trial count.
4 US clinical trials · 2 currently recruiting · #4,115 of 28,707 conditions by registered trial count
Cold Exposure: 4 US clinical trials tracked, 2 recruiting.
Cold Exposure is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Rockefeller University, running 1 of these trials.
Enrollment posture brief
Registry condition cold-exposure
OPEN 2 | RECR 50% | LATE 0 | EARLY 1 | RANK #4115 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Cold Exposure lists 2 open slots (50% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cold Exposure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cold Exposure is recruiting above its size-band peers.
2 of 4 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
4 total, page 1 of 1
Thermogenic Silencer Regulatory Factors in Humans
Rockefeller University
NCT06424132
Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure
Indiana University
NCT05822141
The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold
United States Army Research Institute of Environmental Medicine
NCT06784531
Oxytocin on Cold Water Task Performance and Recovery
Florida Institute for Human and Machine Cognition
NCT04738838
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Cold Exposure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cold Exposure trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cold Exposure page
4 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Cold Exposure trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Rockefeller University sponsors the most Cold Exposure trials on record, review their full trial history before evaluating a specific study. See Rockefeller University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cold Exposure condition card totals 4 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.