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NCT05530317 · ClinicalTrials.gov registry record · NA

CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19

A NA study of COVID-19 and Long COVID, sponsored by University of California, San Francisco.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT05530317 is a NA study of COVID-19 and Long COVID that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 55,214-participant average among 203 other COVID-19 trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05530317, a NA study of COVID-19 and Long COVID, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The goal of this proof-of-concept clinical trial is to determine whether cardiac rehabilitation improves exercise capacity and chronotropic (heart rate) response to exercise among people with Long COVID. The study will include individuals with confirmed SARS-CoV-2 infection, symptoms not present prior to COVID-19 that are persistent for at least 3 months after acute infection ("Long COVID"), and who have reduced exercise capacity less than predicted and reduced heart rate response during cardiopulmonary exercise testing (CPET). In addition to the primary outcome of change in peak VO2, secondary outcomes will include change in symptoms including autonomic symptoms (COMPASS-31), anxiety (GAD-7), depression (PHQ-9), endothelial function with brachial artery flow-mediated dilation, and satisfaction (net-promotor score).

Conditions Studied

Interventions

  • BEHAVIORAL Cardiac Rehabilitation

Study Locations (1)

California

  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2022-12-21
Est. Completion 2025-09
Phase NA

What the Registry Record Tells You About NCT05530317

The ClinicalTrials.gov registry entry for NCT05530317 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 55,214-participant average among 203 other COVID-19 trials with a reported enrollment target (100% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with COVID-19 appearing as the primary indexed condition, and to 1 intervention - of which Cardiac Rehabilitation is the first listed.

NCT05530317 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05530317 about?

NCT05530317 is a clinical study titled "CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19". The goal of this proof-of-concept clinical trial is to determine whether cardiac rehabilitation improves exercise capacity and chronotropic (heart rate) response to exercise among people with Long COVID. The study will include individuals with confirmed SARS-CoV-2 infection, symptoms not present pri...

What is the current status of trial NCT05530317?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-12-21. Estimated completion is 2025-09.

What conditions does trial NCT05530317 study?

This clinical trial studies the following conditions: COVID-19, Long COVID.

What interventions are being tested in trial NCT05530317?

The interventions under investigation include: Cardiac Rehabilitation (BEHAVIORAL).

Who is sponsoring clinical trial NCT05530317?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05530317 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.