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NCT05530317 · ClinicalTrials.gov registry record · NA
CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19
A NA study of COVID-19 and Long COVID, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05530317: Recruiting NA study of COVID-19 and Long COVID, sponsored by University of California, San Francisco.
NCT05530317 is a NA study of COVID-19 and Long COVID that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 38,465-participant average among 298 other COVID-19 trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05530317, a NA study of COVID-19 and Long COVID, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this proof-of-concept clinical trial is to determine whether cardiac rehabilitation improves exercise capacity and chronotropic (heart rate) response to exercise among people with Long COVID. The study will include individuals with confirmed SARS-CoV-2 infection, symptoms not present prior to COVID-19 that are persistent for at least 3 months after acute infection ("Long COVID"), and who have reduced exercise capacity less than predicted and reduced heart rate response during cardiopulmonary exercise testing (CPET). In addition to the primary outcome of change in peak VO2, secondary outcomes will include change in symptoms including autonomic symptoms (COMPASS-31), anxiety (GAD-7), depression (PHQ-9), endothelial function with brachial artery flow-mediated dilation, and satisfaction (net-promotor score).
Primary Outcome
Adjusted heart rate reserve (peak HR-rest HR)/(220-age-rest HR) achieved during symptom-limited maximal cardiopulmonary testing performed with cycle ergometer
Conditions Studied
Interventions
- BEHAVIORAL Cardiac Rehabilitation
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-12-21 |
| Est. Completion | 2025-09 |
| Phase | NA |
What NCT05530317 shows while recruiting
NCT05530317 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 38,465-participant average among 298 other COVID-19 trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with COVID-19 appearing as the primary indexed condition, and to 1 intervention - of which Cardiac Rehabilitation is the first listed.
NCT05530317 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05530317 about?
NCT05530317 is a clinical study titled "CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19". The goal of this proof-of-concept clinical trial is to determine whether cardiac rehabilitation improves exercise capacity and chronotropic (heart rate) response to exercise among people with Long COVID. The study will include individuals with confirmed SARS-CoV-2 infection, symptoms not present pri...
What is the current status of trial NCT05530317?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-12-21. Estimated completion is 2025-09.
What conditions does trial NCT05530317 study?
This clinical trial studies the following conditions: COVID-19, Long COVID.
What interventions are being tested in trial NCT05530317?
The interventions under investigation include: Cardiac Rehabilitation (BEHAVIORAL).
Who is sponsoring clinical trial NCT05530317?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05530317 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for COVID-19
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05530317's enrollment target sits among peer trials
20 279th of 298 higher than 14 of 298 other COVID-19 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other COVID-19 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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