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NCT06386146 · ClinicalTrials.gov registry record · Phase 1

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

A Phase 1 study of Solid Tumors, sponsored by Jacobio Pharmaceuticals Co..

Recruiting
Registry status
Phase 1
Development phase
144
Enrollment target
13
Study locations

NCT06386146 is a Phase 1 study of Solid Tumors that is actively recruiting participants, run by Jacobio Pharmaceuticals Co.. The registered enrollment target is 144 participants, below the 283-participant average among 125 other Solid Tumors trials with a reported enrollment target (49% lower). The trial reports 13 study locations across 10 states.

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The verdict

NCT06386146, a Phase 1 study of Solid Tumors, is actively recruiting participants, sponsored by Jacobio Pharmaceuticals Co..

RECRUITING
Registry status
Phase 1
Development phase
144 participants
Enrollment target
13
Study locations

Study Summary

This study is to evaluate the efficacy and safety of JAB-30355 in adult participants with advanced solid tumors harboring TP53 Y220C mutation.

Conditions Studied

Solid Tumors

Interventions

  • DRUG JAB-30355

Study Locations (13)

Beijing Municipality

  • Research Site - Beijing
  • Research Site - Beijing
  • Research Site - Beijing

Ohio

  • Research site - Canton
  • Research site - Cleveland

Colorado

  • Research Site - Denver

Florida

  • Research site - Lake Mary

Missouri

  • Research site - St Louis

Tennessee

  • Research Site - Nashville

Texas

  • Research site - Houston

Guangdong

  • Research Site - Guangzhou

Trial Details

FieldValue
Enrollment Target 144 participants
Start Date 2024-07-24
Est. Completion 2027-07
Phase Phase 1

Sponsor

Jacobio Pharmaceuticals Co.

7 total trials

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What the Registry Record Tells You About NCT06386146

The ClinicalTrials.gov registry entry for NCT06386146 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 144 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 283-participant average among 125 other Solid Tumors trials with a reported enrollment target (49% lower). The listed sponsor is Jacobio Pharmaceuticals Co., which has 7 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which JAB-30355 is the first listed.

NCT06386146 reports 13 study locations spanning 10 distinct geographic areas - top geographies include Beijing Municipality, Ohio, Colorado.

Frequently Asked Questions

What is clinical trial NCT06386146 about?

NCT06386146 is a clinical study titled "JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation". This study is to evaluate the efficacy and safety of JAB-30355 in adult participants with advanced solid tumors harboring TP53 Y220C mutation.

What is the current status of trial NCT06386146?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 144 participants. The study started on 2024-07-24. Estimated completion is 2027-07.

What conditions does trial NCT06386146 study?

This clinical trial studies the following conditions: Solid Tumors.

What interventions are being tested in trial NCT06386146?

The interventions under investigation include: JAB-30355 (DRUG).

Who is sponsoring clinical trial NCT06386146?

This trial is sponsored by Jacobio Pharmaceuticals Co., which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06386146 being conducted?

This trial has 13 study locations across Colorado, Florida, Missouri, Ohio, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.