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NCT06351098 · ClinicalTrials.gov registry record · NA
Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition
A NA study of Memory, sponsored by University of Maryland, College Park.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 2
- Study locations
NCT06351098: Recruiting NA study of Memory, sponsored by University of Maryland, College Park.
NCT06351098 is a NA study of Memory that is actively recruiting participants, run by University of Maryland, College Park. The registered enrollment target is 180 participants, above the 63-participant average among 15 other Memory trials with a reported enrollment target (186% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06351098, a NA study of Memory, is actively recruiting participants, sponsored by University of Maryland, College Park.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 2
- Study locations
Study Summary
To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the researchers will assess memory, memory change over a nap and equivalent waking interval, sleep physiology of the nap, and brain structure and function (using Magnetic Resonance Imagining or MRI). Additionally, overnight sleep physiology will be assessed in all participants. Waves will take place approximately every 6 months. For all children, three waves will be collected. With these data, the researchers will address the following aims: * Examine neural markers that predict the sleep transition (Aim 1); * Examine changes in sleep-dependent memory processing (mnemonic discrimination) over both nap and overnight sleep intervals, across the sleep transition (Aim 2); * Examine changes in sleep microstructure in both nap and overnight sleep across the sleep transition (Aim 3) * Examine interrelations among brain, memory and sleep microstructure across the sleep transition (Aim 4)
Primary Outcome
Memory will be assessed using the Mnemonic Similarity Task (MST), before and after nap/wake and overnight sleep. The specific variable of interest is the lure discrimination index, which refers to the probability of "Similar" responses to lure items minus the probability of "Similar" responses given to foils.
Conditions Studied
Interventions
- BEHAVIORAL nap
Study Locations (2)
Maryland
- University of Maryland - College Park
Massachusetts
- University of Massachusetts - Amherst
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2023-11-05 |
| Est. Completion | 2028-06 |
| Phase | NA |
What NCT06351098 shows while recruiting
NCT06351098 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 63-participant average among 15 other Memory trials with a reported enrollment target (186% higher).
The record links to 1 condition, with Memory appearing as the primary indexed condition, and to 1 intervention - of which nap is the first listed.
NCT06351098 reports a single indexed study location in Maryland, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06351098 about?
NCT06351098 is a clinical study titled "Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition". To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the research...
What is the current status of trial NCT06351098?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2023-11-05. Estimated completion is 2028-06.
What conditions does trial NCT06351098 study?
This clinical trial studies the following conditions: Memory.
What interventions are being tested in trial NCT06351098?
The interventions under investigation include: nap (BEHAVIORAL).
Who is sponsoring clinical trial NCT06351098?
This trial is sponsored by University of Maryland, College Park, which has 46 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06351098 being conducted?
This trial has 2 study locations across Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Memory
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06351098's enrollment target sits among peer trials
180 2nd of 15 the highest of 15 other Memory trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Memory trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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