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NCT06889961 · ClinicalTrials.gov registry record · NA

Effect of Daily Mixed Spice Consumption on Memory Function

A NA study of Cognitive Function and Memory, sponsored by University of California, Los Angeles.

Recruiting
Registry status
NA
Development phase
50
Enrollment target
1
Study location

NCT06889961: Recruiting NA study of Cognitive Function and Memory, sponsored by University of California, Los Angeles.

NCT06889961 is a NA study of Cognitive Function and Memory that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 50 participants, below the 495-participant average among 20 other Cognitive Function trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06889961, a NA study of Cognitive Function and Memory, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

The aging process entails a multitude of structural and functional alterations within the brain, culminating in a gradual and progressive decline in cognitive function. Recent research has indicated that various spices may hold the key to enhancing brain health and combating the effects of aging on cognitive abilities. The hypothesis is that a mixture of spices, acknowledged for their reported memory protection potential, may yield a more potent beneficial effect on memory function than a single spice. The spice mixture will be used at culinary dose, and therefore side effects are anticipated. In this study, the effects of spice mixture will be evaluated, as well as their anti-oxidant, and anti-inflammatory properties. The proposed pilot study will include 50 adults (ages 50-80), exhibiting typical age-related mild cognitive decline, excluding dementia or major neurocognitive disorders. They will be randomized 1:1 assigned into a daily intake of either 4.00 g spice mixture capsules or 4.00 g maltodextrin capsules over 3 months, and explore the sustainable effect over 3 additional months. The changes in symptoms of cognition, fatigue, and mood symptoms of the spice group vs. placebo group will be compared. The outcome of the investigation of the effects of mixed spice consumption will provide important novel information on dietary recommendation of spice to preserve cognitive function in aging population.

Primary Outcome

Verbal Episodic Memory (Rey Auditory Verbal Learning Test (RAVLT)-Revised, number of words correctly recalled after the long delay).

Interventions

  • OTHER Placebo
  • DIETARY_SUPPLEMENT Mixed spices

Study Locations (1)

California

  • UCLA Center for Human Nutrition - Los Angeles

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-02-21
Est. Completion 2027-02-21
Phase NA

What NCT06889961 shows while recruiting

NCT06889961 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 495-participant average among 20 other Cognitive Function trials with a reported enrollment target (90% lower).

The record links to 2 conditions, with Cognitive Function appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06889961 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06889961 about?

NCT06889961 is a clinical study titled "Effect of Daily Mixed Spice Consumption on Memory Function". The aging process entails a multitude of structural and functional alterations within the brain, culminating in a gradual and progressive decline in cognitive function. Recent research has indicated that various spices may hold the key to enhancing brain health and combating the effects of aging on ...

What is the current status of trial NCT06889961?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-02-21. Estimated completion is 2027-02-21.

What conditions does trial NCT06889961 study?

This clinical trial studies the following conditions: Cognitive Function, Memory.

What interventions are being tested in trial NCT06889961?

The interventions under investigation include: Placebo (OTHER), Mixed spices (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT06889961?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06889961 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cognitive Function

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06889961's enrollment target sits among peer trials

50 13th of 20 higher than 7 of 20 other Cognitive Function trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cognitive Function trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06889961, the US trial registry maintained by the National Library of Medicine. NCT06889961 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.