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NCT05229341 · ClinicalTrials.gov registry record · NA
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
A NA study of Thyroid Gland Carcinoma, sponsored by City of Hope Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 1,450
- Enrollment target
- 1
- Study location
NCT05229341: Recruiting NA study of Thyroid Gland Carcinoma, sponsored by City of Hope Medical Center.
NCT05229341 is a NA study of Thyroid Gland Carcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 1,450 participants, above the 314-participant average among 3 other Thyroid Gland Carcinoma trials with a reported enrollment target (362% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05229341, a NA study of Thyroid Gland Carcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,450 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer. This test will use needle biopsies (small collections of tissue with a needle) from the thyroid to determine whether the participant has a malignant (cancer) or benign (not showing cancer) thyroid tumor. The information learned from this trial may help develop a more accurate test so that patients do not have unnecessary surgeries for nodules that are thought to be suspicious but are actually benign.
Primary Outcome
The sensitivity of DDMS-2 will be estimated by taking the ratio of the number of true thyroid cancer specimens diagnosed as cancer by DDMS and the total number of thyroid cancer specimens. Will also determine the 95% confidence intervals.
Conditions Studied
Interventions
- OTHER Electronic Health Record Review
- PROCEDURE Diagnostic Procedure
- PROCEDURE Needle Biopsy
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,450 participants |
| Start Date | 2021-10-22 |
| Est. Completion | 2026-10-22 |
| Phase | NA |
What NCT05229341 shows while recruiting
NCT05229341 is an interventional study that assigns participants to a tested intervention. Its 1,450 participants enrollment target places it among the larger protocols in the corpus, above the 314-participant average among 3 other Thyroid Gland Carcinoma trials with a reported enrollment target (362% higher).
The record links to 1 condition, with Thyroid Gland Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Electronic Health Record Review is the first listed.
NCT05229341 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05229341 about?
NCT05229341 is a clinical study titled "Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules". This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer. This test will use needle biopsies (small collections of tissue with a needle) from the thyroid to de...
What is the current status of trial NCT05229341?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,450 participants. The study started on 2021-10-22. Estimated completion is 2026-10-22.
What conditions does trial NCT05229341 study?
This clinical trial studies the following conditions: Thyroid Gland Carcinoma.
What interventions are being tested in trial NCT05229341?
The interventions under investigation include: Electronic Health Record Review (OTHER), Diagnostic Procedure (PROCEDURE), Needle Biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT05229341?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05229341 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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