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Early Detection of Advanced Adenomas and Colorectal Cancer
NCT06342440 · View on ClinicalTrials.gov ↗
Study Summary
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST DENEB
Study Locations (6)
Other
- The First Affiliated Hospital of Dalian Medical University — Dalian
- IRCCS San Raffaele — Milan
- Mie University — Mie
- Barcelona University — Barcelona
California
- City of Hope Medical Center — Monrovia
- University of California San Diego — San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2020-03-15 |
| Est. Completion | 2026-06-18 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06342440
The ClinicalTrials.gov registry entry for NCT06342440 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is City of Hope Medical Center, which has 771 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention — of which DENEB is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06342440 reports 6 study locations spanning 2 distinct geographic areas — top geographies include Other, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06342440 about?
NCT06342440 is a clinical study titled "Early Detection of Advanced Adenomas and Colorectal Cancer". This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
What is the current status of trial NCT06342440?
This trial is currently recruiting. The enrollment target is 2,000 participants. The study started on 2020-03-15. Estimated completion is 2026-06-18.
What conditions does trial NCT06342440 study?
This clinical trial studies the following conditions: Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Disorders, Colorectal Cancer Stage II. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06342440?
The interventions under investigation include: DENEB (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06342440?
This trial is sponsored by City of Hope Medical Center, which has 771 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06342440 being conducted?
This trial has 6 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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