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NCT06249178 · ClinicalTrials.gov registry record
EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)
A clinical trial of Preeclampsia, sponsored by Ohio State University.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT06249178 is a study of Preeclampsia that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 1,000 participants, below the 1,256-participant average among 39 other Preeclampsia trials with a reported enrollment target (20% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06249178, a study of Preeclampsia, is actively recruiting participants, sponsored by Ohio State University.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this prospective observational cohort study of pregnant people at-risk of preeclampsia receiving aspirin as part of clinical care or a planned randomized controlled trial of 81mg vs. 162mg of aspirin is to generate proteomic data to show a distinct maternal and fetal Extracellular Vesicle (EV) proteome profile with aspirin treatment, and develop and validate a multi-marker panel for the monitoring of placental function in people at-risk of Preeclampsia and in response to aspirin treatment. The primary research question is: 1\. Does the maternal and fetal Positive for Placental Alkaline Phosphatase (PLAP+) Extracellular Vesicle (EV) proteome profile in the 2nd and 3rd trimester of pregnancy differ between people who receive aspirin and develop (or not) preeclampsia? Participants will be asked to give blood samples up to four times during and at the end of their pregnancy.
Conditions Studied
Study Locations (1)
Ohio
- The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2024-07-02 |
| Est. Completion | 2028-09-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06249178
The ClinicalTrials.gov registry entry for NCT06249178 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,256-participant average among 39 other Preeclampsia trials with a reported enrollment target (20% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Preeclampsia appearing as the primary indexed condition, and to 0 interventions.
NCT06249178 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT06249178 about?
NCT06249178 is a clinical study titled "EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)". The goal of this prospective observational cohort study of pregnant people at-risk of preeclampsia receiving aspirin as part of clinical care or a planned randomized controlled trial of 81mg vs. 162mg of aspirin is to generate proteomic data to show a distinct maternal and fetal Extracellular Vesicl...
What is the current status of trial NCT06249178?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2024-07-02. Estimated completion is 2028-09-01.
What conditions does trial NCT06249178 study?
This clinical trial studies the following conditions: Preeclampsia.
Who is sponsoring clinical trial NCT06249178?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06249178 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
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