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NCT06168461 · ClinicalTrials.gov registry record · Early Phase 1
Daily Aspirin Treatment After Preeclampsia
A Early Phase 1 study of Preeclampsia, sponsored by Anna Stanhewicz, PhD.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT06168461: Recruiting Early Phase 1 study of Preeclampsia, sponsored by Anna Stanhewicz, PhD.
NCT06168461 is a Early Phase 1 study of Preeclampsia that is actively recruiting participants, run by Anna Stanhewicz, PhD. The registered enrollment target is 40 participants, below the 1,125-participant average among 48 other Preeclampsia trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06168461, a Early Phase 1 study of Preeclampsia, is actively recruiting participants, sponsored by Anna Stanhewicz, PhD.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent this disease progression. This study addresses this public health issue by examining whether starting low dose aspirin therapy after pregnancy is an effective treatment for lasting blood vessel damage in order to inform better clinical management of cardiovascular disease risk in women who have had preeclampsia.
Primary Outcome
skin blood flow response to acetylcholine delivered via intradermal microdialysis
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Aspirin
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-11-01 |
| Est. Completion | 2026-06 |
| Phase | Early Phase 1 |
What NCT06168461 shows while recruiting
NCT06168461 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,125-participant average among 48 other Preeclampsia trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Preeclampsia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06168461 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT06168461 about?
NCT06168461 is a clinical study titled "Daily Aspirin Treatment After Preeclampsia". Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment s...
What is the current status of trial NCT06168461?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2023-11-01. Estimated completion is 2026-06.
What conditions does trial NCT06168461 study?
This clinical trial studies the following conditions: Preeclampsia.
What interventions are being tested in trial NCT06168461?
The interventions under investigation include: Placebo (DRUG), Aspirin (DRUG).
Who is sponsoring clinical trial NCT06168461?
This trial is sponsored by Anna Stanhewicz, PhD, which has 14 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06168461 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Preeclampsia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06168461's enrollment target sits among peer trials
40 43rd of 48 higher than 4 of 48 other Preeclampsia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Preeclampsia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Prenatal Aspirin and Postpartum Vascular Function
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-
Predictors of Aspirin Failure in Preeclampsia Prevention
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MR and Inflammation After Preeclampsia
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Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)
COMPLETED · Early Phase 1
-
Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories
RECRUITING · Phase 2
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