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Preeclampsia clinical trials
Every US clinical trial registered for Preeclampsia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
40 US clinical trials · 21 currently recruiting
The research picture
Preeclampsia has 40 registered US clinical trials, 21 of them open to new participants right now — about 53% of the total.
- 21
- recruiting participants now
- 53%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Anna Stanhewicz, PhD
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
The Preeclampsia Registry
Preeclampsia Foundation
NCT06377878
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Ohio State University
NCT06468202
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
The George Washington University Biostatistics Center
NCT03487185
EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)
Ohio State University
NCT06249178
Exercise Testing After Preeclampsia
Vanderbilt University Medical Center
NCT06741436
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
University of Pittsburgh
NCT05655936
Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)
Thomas Jefferson University
NCT06826859
Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories
Massachusetts General Hospital
NCT07041281
The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
University of Alabama at Birmingham
NCT05676476
Predictors of Aspirin Failure in Preeclampsia Prevention
Rockefeller University
NCT05709483
Preventing Obstetric Complications With Dietary Intervention
Medical College of Wisconsin
NCT06320054
Effects of High Altitude on AMPK Activation
University of Colorado, Denver
NCT02391519
AtorvaStatin Postpartum and Reduction of Cardiovascular risK
Ohio State University
NCT06632379
Exosome Cargo From Preeclampsia Patients
University of Alabama at Birmingham
NCT04154332
Prenatal Aspirin and Postpartum Vascular Function
Anna Stanhewicz, PhD
NCT05653973
Placental Imaging Techniques
Carilion Clinic
NCT06861309
Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia
University of Tennessee Graduate School of Medicine
NCT06802861
Daily Aspirin Treatment After Preeclampsia
Anna Stanhewicz, PhD
NCT06168461
Vascular Effects of High-Salt After Preeclampsia
Anna Stanhewicz, PhD
NCT06749418
Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy
University of Utah
NCT05826925
Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
Mayo Clinic
NCT06333652
MIRACLE of LIFE Study
Mirvie
NCT06074601
Low Dose Aspirin Alerts in High-Risk Pregnancies
Geisinger Clinic
NCT05802940
Preeclampsia Postpartum Antihypertensive Treatment
Medical College of Wisconsin
NCT04298034
Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)
The Miriam Hospital
NCT02412696
Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients
University of Virginia
NCT05514847
MR and Inflammation After Preeclampsia
Anna Stanhewicz, PhD
NCT07345845
Preeclampsia Educational Program Study (PrEPS)
MemorialCare Health System
NCT06373367
Family Study on Preeclampsia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00344162
Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia
University of Mississippi Medical Center
NCT00583635
Nudge to Drive Transitions of Care
University of Pennsylvania
NCT04660032
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
University of Pittsburgh
NCT03749746
Antenatal Platelet Response On Aspirin and Correlation With HDP (Hypertensive Disorders of Pregnancy)
Thomas Jefferson University
NCT04295850
Randomized Clinical Trial to Increase Physical Activity After a a Hypertensive Pregnancy
University of Pennsylvania
NCT04119232
App-based Remote Blood Pressure Monitoring
Women and Infants Hospital of Rhode Island
NCT05595629
Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)
University of Colorado, Denver
NCT02221830
Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients
Milton S. Hershey Medical Center
NCT01261884
Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)
University of Mississippi Medical Center
NCT00653809
Pravastatin for Prevention of Preeclampsia
The University of Texas Medical Branch, Galveston
NCT01717586
User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study
University of Colorado, Denver
NCT02384226
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Preeclampsia Trial Landscape
ClinicalTrials.gov lists 40 US studies indexed under Preeclampsia, and 21 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Preeclampsia shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Preeclampsia is led by Anna Stanhewicz, PhD with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 40 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Preeclampsia?
PlainTrial tracks 40 US clinical trials for Preeclampsia, of which 21 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Preeclampsia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.