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ClinicalTrials.gov 29 recruiting now full pipeline

Preeclampsia: full-pipeline trial registry

29 of 49 indexed Preeclampsia trials are currently recruiting.

Corpus placement: #281 of 28,707 conditions by registered trial count.

49 US clinical trials · 29 currently recruiting · #281 of 28,707 conditions by registered trial count

Preeclampsia: 49 US clinical trials tracked, 29 recruiting.

Preeclampsia is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Anna Stanhewicz, PhD, running 4 of these trials.

Enrollment posture brief

Registry condition preeclampsia

OPEN 29 | RECR 59% | LATE 8 | EARLY 10 | RANK #281 | SPON 4

Nearest open-share peer: Movement Disorders (59% recruiting · 27 trials)

Preeclampsia (this)59%Diet, Healthy49%Duchenne Muscular Dystrophy44.9%Chronic Disease36.7%Arthritis30.6%
Open-enrollment share among volume-matched conditions near Preeclampsia

Preeclampsia lists 29 open slots (59% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Preeclampsia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Preeclampsia is recruiting above its size-band peers.

    29 of 49 indexed trials (59.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Preeclampsia trials is spread across many organizations.

    Anna Stanhewicz, PhD accounts for 4 of 49 trials (8.2%). 35 distinct sponsors appear on at least one study for this condition label.

  3. Typical Preeclampsia enrolment sits around 132 participants.

    Median target enrolment is 132 among the 49 trials that report a genuine target (sentinel values excluded). 18 of those (36.7%) plan for fewer than 100 participants.

  4. Preeclampsia splits between interventional and observational designs.

    34 interventional and 15 observational studies make up this index (69.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 22Phase 33Phase 45

Open and recent trials

49 total, page 1 of 1

RECRUITING 20,000 participants

The Preeclampsia Registry

Preeclampsia Foundation

NCT06377878

RECRUITING Phase 4 10,742 participants

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

Ohio State University

NCT06468202

RECRUITING NA 1,500 participants

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

The George Washington University Biostatistics Center

NCT03487185

RECRUITING Phase 3 1,150 participants

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

University of Pennsylvania

NCT06408181

RECRUITING 1,100 participants

Multi-Omics for Maternal Health After Preeclampsia

University of California, San Diego

NCT06340152

RECRUITING 1,000 participants

EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)

Ohio State University

NCT06249178

RECRUITING 500 participants

Exercise Testing After Preeclampsia

Vanderbilt University Medical Center

NCT06741436

RECRUITING NA 454 participants

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

University of Pittsburgh

NCT05655936

RECRUITING Phase 1 400 participants

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

Thomas Jefferson University

NCT06826859

RECRUITING NA 250 participants

Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women

Christiana Care Health Services

NCT06180811

RECRUITING NA 224 participants

Physical Activity to Mitigate PreEclampsia Risk

East Carolina University

NCT06319014

RECRUITING Phase 2 204 participants

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

Massachusetts General Hospital

NCT07041281

RECRUITING Phase 4 200 participants

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

University of Michigan

NCT06785116

RECRUITING 166 participants

Mechanisms of Pregnancy Vascular Adaptations

University of Wisconsin, Madison

NCT03806283

RECRUITING NA 132 participants

The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.

University of Alabama at Birmingham

NCT05676476

RECRUITING Early Phase 1 130 participants

Predictors of Aspirin Failure in Preeclampsia Prevention

Rockefeller University

NCT05709483

RECRUITING NA 120 participants

Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy

Northwestern University

NCT06523569

RECRUITING NA 100 participants

Preventing Obstetric Complications With Dietary Intervention

Medical College of Wisconsin

NCT06320054

RECRUITING 84 participants

Effects of High Altitude on AMPK Activation

University of Colorado, Denver

NCT02391519

RECRUITING Phase 4 76 participants

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

Ohio State University

NCT06632379

RECRUITING 64 participants

Exosome Cargo From Preeclampsia Patients

University of Alabama at Birmingham

NCT04154332

RECRUITING Early Phase 1 60 participants

Prenatal Aspirin and Postpartum Vascular Function

Anna Stanhewicz, PhD

NCT05653973

RECRUITING 60 participants

Placental Imaging Techniques

Carilion Clinic

NCT06861309

RECRUITING Phase 4 60 participants

Treatment With Aspirin After Preeclampsia: TAP Trial

Malamo Countouris

NCT06281665

RECRUITING 50 participants

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

University of Tennessee Graduate School of Medicine

NCT06802861

RECRUITING Early Phase 1 40 participants

Daily Aspirin Treatment After Preeclampsia

Anna Stanhewicz, PhD

NCT06168461

RECRUITING Early Phase 1 40 participants

Vascular Effects of High-Salt After Preeclampsia

Anna Stanhewicz, PhD

NCT06749418

RECRUITING NA 30 participants

Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy

University of Utah

NCT05826925

RECRUITING Phase 2 14 participants

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Mayo Clinic

NCT06333652

ACTIVE NOT RECRUITING 10,000 participants

MIRACLE of LIFE Study

Mirvie

NCT06074601

ACTIVE NOT RECRUITING NA 839 participants

Low Dose Aspirin Alerts in High-Risk Pregnancies

Geisinger Clinic

NCT05802940

ACTIVE NOT RECRUITING Phase 3 788 participants

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

JHSPH Center for Clinical Trials

NCT04551807

ACTIVE NOT RECRUITING Phase 3 300 participants

Preeclampsia Postpartum Antihypertensive Treatment

Medical College of Wisconsin

NCT04298034

ACTIVE NOT RECRUITING NA 262 participants

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

The Miriam Hospital

NCT02412696

ACTIVE NOT RECRUITING Phase 4 150 participants

Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients

University of Virginia

NCT05514847

ACTIVE NOT RECRUITING Early Phase 1 40 participants

MR and Inflammation After Preeclampsia

Anna Stanhewicz, PhD

NCT07345845

ACTIVE NOT RECRUITING NA 36 participants

Preeclampsia Educational Program Study (PrEPS)

MemorialCare Health System

NCT06373367

COMPLETED 1,000 participants

Family Study on Preeclampsia

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00344162

COMPLETED 684 participants

Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia

University of Mississippi Medical Center

NCT00583635

COMPLETED NA 224 participants

Nudge to Drive Transitions of Care

University of Pennsylvania

NCT04660032

COMPLETED NA 148 participants

Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia

University of Pittsburgh

NCT03749746

COMPLETED 130 participants

Antenatal Platelet Response On Aspirin and Correlation With HDP (Hypertensive Disorders of Pregnancy)

Thomas Jefferson University

NCT04295850

COMPLETED NA 128 participants

Randomized Clinical Trial to Increase Physical Activity After a a Hypertensive Pregnancy

University of Pennsylvania

NCT04119232

COMPLETED NA 120 participants

App-based Remote Blood Pressure Monitoring

Women and Infants Hospital of Rhode Island

NCT05595629

COMPLETED Early Phase 1 66 participants

Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)

University of Colorado, Denver

NCT02221830

COMPLETED NA 66 participants

Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients

Milton S. Hershey Medical Center

NCT01261884

COMPLETED 52 participants

Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)

University of Mississippi Medical Center

NCT00653809

COMPLETED Phase 1 48 participants

Pravastatin for Prevention of Preeclampsia

The University of Texas Medical Branch, Galveston

NCT01717586

COMPLETED 26 participants

User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study

University of Colorado, Denver

NCT02384226

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 2
Phase 3 3
Phase 4 5

Named interventions

Most-linked intervention names on Preeclampsia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Eplerenone Drug
2 trials
Aspirin 81 mg Drug
2 trials
Aspirin 162 mg Drug
2 trials
Aspirin Drug
2 trials
Heart Health 4 New Moms Behavioral
1 trials
Home Blood Pressure Monitoring Behavioral
1 trials
Exercise support Behavioral
1 trials

US sites by state

Facility locations filed on Preeclampsia trials. A trial with sites in several states counts in each.

Pennsylvania 16 trials
Ohio 6 trials
California 6 trials
Texas 5 trials
Illinois 5 trials
Wisconsin 4 trials
Rhode Island 4 trials
New York 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Preeclampsia page

49 registered trials, 29 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Preeclampsia condition card totals 49 registered trials; most-linked intervention Placebo; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.