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NCT06234631 · ClinicalTrials.gov registry record · Phase 2
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
A Phase 2 study of Osteoarthritis, Knee and Knee Replacement Surgery, sponsored by Chad Brummett.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 380
- Enrollment target
- 2
- Study locations
NCT06234631 is a Phase 2 study of Osteoarthritis, Knee and Knee Replacement Surgery that is actively recruiting participants, run by Chad Brummett. The registered enrollment target is 380 participants, below the 576-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target (34% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT06234631, a Phase 2 study of Osteoarthritis, Knee and Knee Replacement Surgery, is actively recruiting participants, sponsored by Chad Brummett.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 380 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflammation and other related symptoms, after knee replacement surgery. The information collected in this study is necessary to help understand whether CBD may be a useful medication before and/or after surgery. The study hypothesis is that CBD exerts opioid-sparing effects through anti-inflammatory, analgesic, and anxiolytic mechanisms.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Epidiolex oral solution
Study Locations (2)
Michigan
- University of Michigan - Ann Arbor
- Henry Ford Health System - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 380 participants |
| Start Date | 2024-03-13 |
| Est. Completion | 2029-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06234631
The ClinicalTrials.gov registry entry for NCT06234631 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 380 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 576-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target (34% lower). The listed sponsor is Chad Brummett, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06234631 reports 2 study locations spanning 1 distinct geographic area - top geographies include Michigan.
Frequently Asked Questions
What is clinical trial NCT06234631 about?
NCT06234631 is a clinical study titled "Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty". The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflammation and other related symptoms, after knee replacement surgery. The information collected in this study is necessary to help understand whe...
What is the current status of trial NCT06234631?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 380 participants. The study started on 2024-03-13. Estimated completion is 2029-01.
What conditions does trial NCT06234631 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Knee Replacement Surgery.
What interventions are being tested in trial NCT06234631?
The interventions under investigation include: Placebo (OTHER), Epidiolex oral solution (DRUG).
Who is sponsoring clinical trial NCT06234631?
This trial is sponsored by Chad Brummett, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06234631 being conducted?
This trial has 2 study locations across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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