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NCT06214065 · ClinicalTrials.gov registry record · NA

Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)

A NA study of Autism Spectrum Disorder, sponsored by Yale University.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT06214065 is a NA study of Autism Spectrum Disorder that is actively recruiting participants, run by Yale University. The registered enrollment target is 80 participants, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06214065, a NA study of Autism Spectrum Disorder, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

The goal of this observational study is to test the modulation effect of different transcranial magnetic stimulation (TMS) on the neural network supporting our ability to create mental representations of others (also known as mentalizing) in young adults with autism. The main question it aims to answers is can stimulation of the right temporoparietal junction can change brain activity related to mentalizing during social interaction in the stimulation area and other brain areas connected to it. Researchers will compare results to a group of individuals without autism to see if the patterns of neural activity change are similar between the groups. Participants will undergo assessment of their clinical traits and social skills and baseline MRI scan. They will attend three additional visits that include TMS session and functional MRI scans before and right after TMS.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST fMRI
  • DEVICE rTMS

Study Locations (1)

Connecticut

  • Olin Neuropsychiatry Research Center (ONRC) - Hartford

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-04-03
Est. Completion 2027-10
Phase NA

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT06214065

The ClinicalTrials.gov registry entry for NCT06214065 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (41% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 2 interventions - of which fMRI is the first listed.

NCT06214065 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06214065 about?

NCT06214065 is a clinical study titled "Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)". The goal of this observational study is to test the modulation effect of different transcranial magnetic stimulation (TMS) on the neural network supporting our ability to create mental representations of others (also known as mentalizing) in young adults with autism. The main question it aims to ans...

What is the current status of trial NCT06214065?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-04-03. Estimated completion is 2027-10.

What conditions does trial NCT06214065 study?

This clinical trial studies the following conditions: Autism Spectrum Disorder.

What interventions are being tested in trial NCT06214065?

The interventions under investigation include: fMRI (DIAGNOSTIC_TEST), rTMS (DEVICE).

Who is sponsoring clinical trial NCT06214065?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06214065 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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