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NCT06213324 · ClinicalTrials.gov registry record · Phase 4

Neural Circuit Effects of Ketamine in Depression

A Phase 4 study of Major Depressive Disorder, sponsored by Icahn School of Medicine at Mount Sinai.

Recruiting
Registry status
Phase 4
Development phase
120
Enrollment target
1
Study location

NCT06213324 is a Phase 4 study of Major Depressive Disorder that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 120 participants, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (68% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06213324, a Phase 4 study of Major Depressive Disorder, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.

RECRUITING
Registry status
Phase 4
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and depression symptoms.

Conditions Studied

Major Depressive Disorder

Interventions

  • DRUG Placebo
  • DRUG Ketamine

Study Locations (1)

New York

  • Icahn School of Medicine at Mount Sinai - New York

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2024-01-31
Est. Completion 2028-04-30
Phase Phase 4

Sponsor

Icahn School of Medicine at Mount Sinai

708 total trials

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What the Registry Record Tells You About NCT06213324

The ClinicalTrials.gov registry entry for NCT06213324 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 376-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (68% lower). The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06213324 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06213324 about?

NCT06213324 is a clinical study titled "Neural Circuit Effects of Ketamine in Depression". This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and depression symptoms.

What is the current status of trial NCT06213324?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2024-01-31. Estimated completion is 2028-04-30.

What conditions does trial NCT06213324 study?

This clinical trial studies the following conditions: Major Depressive Disorder.

What interventions are being tested in trial NCT06213324?

The interventions under investigation include: Placebo (DRUG), Ketamine (DRUG).

Who is sponsoring clinical trial NCT06213324?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06213324 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.