Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
NCT06200207 · View on ClinicalTrials.gov ↗
Study Summary
The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the study medicine but does not contain any medicine). The treatment participants get is decided by chance. Participant's chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study is expected to last for up to 1 year and 4 months.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Ziltivekimab
Study Locations (20)
Florida
- Clearwater Cardiovascular Consultants — Largo
- Clearwater Cardiovascular Consultants — Largo
- Ocala Cardiovascular Research — Ocala
- Ormond Beach Clinical Research — Ormond Beach
- St Johns Ctr Clin Rsch-St. Aug — Saint Augustine
California
- Valley Clinical Trials, Inc. — Northridge
- Valley Clinical Trials, Inc. — Northridge
- UCI Health — Orange
- South California Heart Spc — Pasadena
Alabama
- Advanced Cardiovascular, LLC — Alexander City
- Eastern Shore Rsrch Inst, LLC — Fairhope
Georgia
- GA Arrhythmia Cons & Rsch Inst — Macon
- Velocity Clin Rsrch - Savannah — Savannah
Maryland
- Maryland Cardiovascular Specialists - Baltimore — Baltimore
- MD Medical Research — Oxon Hill
Michigan
- Cardio and Vascular Assoc-CAVA — Bloomfield Hills
- Millennium Cardiology — Farmington Hills
Arkansas
- Cardiology & Medicine Clinic — Little Rock
Illinois
- Chicago Medical Research LLC — Hazel Crest
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 680 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2027-01-08 |
| Phase | Phase 3 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06200207
The ClinicalTrials.gov registry entry for NCT06200207 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 680 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06200207 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06200207 about?
NCT06200207 is a clinical study titled "A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation". The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the study medicine but does not contain any medicine). The treatment...
What is the current status of trial NCT06200207?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 680 participants. The study started on 2024-04-01. Estimated completion is 2027-01-08.
What conditions does trial NCT06200207 study?
This clinical trial studies the following conditions: Heart Failure, Systemic Inflammation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06200207?
The interventions under investigation include: Placebo (DRUG), Ziltivekimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06200207?
This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06200207 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.