Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06174987 · ClinicalTrials.gov registry record · Phase 3
A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)
A Phase 3 study of Advanced Cancer and Metastatic Cancer, sponsored by Daiichi Sankyo.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 50
- Enrollment target
- 20
- Study locations
NCT06174987: Recruiting Phase 3 study of Advanced Cancer and Metastatic Cancer, sponsored by Daiichi Sankyo.
NCT06174987 is a Phase 3 study of Advanced Cancer and Metastatic Cancer that is actively recruiting participants, run by Daiichi Sankyo. The registered enrollment target is 50 participants, below the 246-participant average among 122 other Advanced Cancer trials with a reported enrollment target (80% lower). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06174987, a Phase 3 study of Advanced Cancer and Metastatic Cancer, is actively recruiting participants, sponsored by Daiichi Sankyo.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 50 participants
- Enrollment target
- 20
- Study locations
Study Summary
This open-label, multicenter, rollover study will provide continued treatment for participants deriving benefit from different therapies received in studies sponsored by Daiichi Sankyo, Inc. (DS) or DS/Astra Zeneca (AZ)-sponsored study (eg. DS8201-A-J101, DS8201-A-U201, DS8201-A-U204, DS8201-A-U207, DS8201-A-U303).
Conditions Studied
Interventions
- DRUG T-DXd
Study Locations (20)
Other
- Flinders Medical Center - Bedford Park
- Monash Medical Center - Melbourne
- Grand Hôpital de Charleroi - Charleroi
- Instituto Aericas - Rio de Janeiro
- A.C. Camargo Cancer Center - São Paulo
- IBCC Nucleo de Pequisa e Ensino - São Paulo
- Institut Gustave Roussy - Villejuif
- Rabin Medical Center - Petah Tikva
- Ospedale San Raffaele - Milan
- Istituto Nazionale Tumori Fondazione G. Pascale - Naples
- National Cancer Center Hospital - Chūō
- Kyungpook National University Chilgok Hospital - Daegu
- National Cancer Center - Gyeonggi-do
- Seoul National University Bundang Hospital - Gyeonggi-do
- Seoul National University Hospital - Jongno-gu
- Severance Hospital, Yonsei University - Seoul
- Asan Medical Center - Seoul
- Samsung Medical Center - Seoul
Florida
- Miami Cancer Institute - Miami
North Carolina
- Duke University - Trent Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-01-05 |
| Est. Completion | 2028-01-17 |
| Phase | Phase 3 |
What NCT06174987 shows while recruiting
NCT06174987 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 246-participant average among 122 other Advanced Cancer trials with a reported enrollment target (80% lower).
The record links to 2 conditions, with Advanced Cancer appearing as the primary indexed condition, and to 1 intervention - of which T-DXd is the first listed.
NCT06174987 names 20 study sites across 3 states, led by Other, Florida, North Carolina.
Frequently Asked Questions
What is clinical trial NCT06174987 about?
NCT06174987 is a clinical study titled "A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)". This open-label, multicenter, rollover study will provide continued treatment for participants deriving benefit from different therapies received in studies sponsored by Daiichi Sankyo, Inc. (DS) or DS/Astra Zeneca (AZ)-sponsored study (eg. DS8201-A-J101, DS8201-A-U201, DS8201-A-U204, DS8201-A-U207,...
What is the current status of trial NCT06174987?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 50 participants. The study started on 2024-01-05. Estimated completion is 2028-01-17.
What conditions does trial NCT06174987 study?
This clinical trial studies the following conditions: Advanced Cancer, Metastatic Cancer.
What interventions are being tested in trial NCT06174987?
The interventions under investigation include: T-DXd (DRUG).
Who is sponsoring clinical trial NCT06174987?
This trial is sponsored by Daiichi Sankyo, which has 236 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06174987 being conducted?
This trial has 20 study locations across Florida, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Advanced Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06174987's enrollment target sits among peer trials
50 86th of 122 higher than 37 of 122 other Advanced Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Advanced Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Sativex® for Relieving Persistent Pain in Patients With Advanced Cancer
COMPLETED · Phase 3
-
Evaluating Disparities in Precision Oncology
RECRUITING
-
BOLSTER: Learning New Skills to Thrive
RECRUITING · NA
-
Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)
RECRUITING · Phase 2
-
Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer
RECRUITING · NA
-
Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI