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NCT06137274 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC
A Phase 2 study of Head and Neck Cancer and Squamous Cell Carcinoma, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- Active
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT06137274: Active Phase 2 study of Head and Neck Cancer and Squamous Cell Carcinoma, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
NCT06137274 is a Phase 2 study of Head and Neck Cancer and Squamous Cell Carcinoma that is active but no longer recruiting, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 25 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06137274, a Phase 2 study of Head and Neck Cancer and Squamous Cell Carcinoma, is active but no longer recruiting, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to determine if it is feasible to use magnetic resonance imaging (MRI) to adjust a portion of radiation therapy for patients with head and neck squamous cell carcinoma . The technique under study will be used to personalize the study treatment based on response, keeping all treatments within standard of care guidelines.
Primary Outcome
Feasibility of MR adaptive boost technique, as defined as achieving a reduction of mean OAR (parotids, submandibular glands, pharynx, oral cavity, tubarial glands, larynx, esophagus, and thyroid) doses greater than 7.5% compared to unadapted CT based plan. If 18 of 25 patients are meet the mean OAR criteria the approach will be considered feasible.
Conditions Studied
Interventions
- RADIATION Intensity-modulated radiotherapy
- OTHER Magnetic Resonance Guidance
Study Locations (1)
Florida
- Moffitt Cancer Center - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-12-14 |
| Est. Completion | 2026-11 |
| Phase | Phase 2 |
What the registry record for NCT06137274 still lists
NCT06137274 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Intensity-modulated radiotherapy is the first listed.
NCT06137274 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06137274 about?
NCT06137274 is a clinical study titled "Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC". The purpose of the study is to determine if it is feasible to use magnetic resonance imaging (MRI) to adjust a portion of radiation therapy for patients with head and neck squamous cell carcinoma . The technique under study will be used to personalize the study treatment based on response, keeping a...
What is the current status of trial NCT06137274?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2023-12-14. Estimated completion is 2026-11.
What conditions does trial NCT06137274 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Squamous Cell Carcinoma.
What interventions are being tested in trial NCT06137274?
The interventions under investigation include: Intensity-modulated radiotherapy (RADIATION), Magnetic Resonance Guidance (OTHER).
Who is sponsoring clinical trial NCT06137274?
This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06137274 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06137274's enrollment target sits among peer trials
25 196th of 250 higher than 47 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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