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NCT06105788 · ClinicalTrials.gov registry record · NA
Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis
A NA study of Knee Osteoarthritis and Knee Pain Chronic, sponsored by University of Texas, El Paso.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06105788: Recruiting NA study of Knee Osteoarthritis and Knee Pain Chronic, sponsored by University of Texas, El Paso.
NCT06105788 is a NA study of Knee Osteoarthritis and Knee Pain Chronic that is actively recruiting participants, run by University of Texas, El Paso. The registered enrollment target is 60 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06105788, a NA study of Knee Osteoarthritis and Knee Pain Chronic, is actively recruiting participants, sponsored by University of Texas, El Paso.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).
Primary Outcome
Pressure pain thresholds (PPT) will be assessed at the wrist and patella. PPT being assessed at a remote body site (e.g., wrist) is to measure central pain sensitivity while PPT being assessed at the location of pain (i.e., knee, patellae) is to assess peripheral pain sensitivity with or without central pain sensitivity. PPT will be assessed using a handheld pressure algometer with 1 cm2 rubber tip. PPT will be defined as the point at which the participant verbally indicated that the pressure fi
Conditions Studied
Interventions
- OTHER Exercise
Study Locations (1)
Texas
- The University of Texas at El Paso - El Paso
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-11-15 |
| Est. Completion | 2025-10-16 |
| Phase | NA |
What NCT06105788 shows while recruiting
NCT06105788 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (80% lower).
The record links to 3 conditions, with Knee Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT06105788 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06105788 about?
NCT06105788 is a clinical study titled "Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis". The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioecono...
What is the current status of trial NCT06105788?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-11-15. Estimated completion is 2025-10-16.
What conditions does trial NCT06105788 study?
This clinical trial studies the following conditions: Knee Osteoarthritis, Knee Pain Chronic, Central Pain Syndrome.
What interventions are being tested in trial NCT06105788?
The interventions under investigation include: Exercise (OTHER).
Who is sponsoring clinical trial NCT06105788?
This trial is sponsored by University of Texas, El Paso, which has 17 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06105788 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06105788's enrollment target sits among peer trials
60 62nd of 101 higher than 37 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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