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NCT06096714 · ClinicalTrials.gov registry record · Early Phase 1
Addictive Threshold of Nicotine
A Early Phase 1 study of Smoking Addiction, sponsored by Yale University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT06096714: Recruiting Early Phase 1 study of Smoking Addiction, sponsored by Yale University.
NCT06096714 is a Early Phase 1 study of Smoking Addiction that is actively recruiting participants, run by Yale University. The registered enrollment target is 36 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06096714, a Early Phase 1 study of Smoking Addiction, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine the nicotine threshold dose(s) for discrimination, subjective-rewarding effects, -and reinforcement in smokers with different levels of dependence.
Primary Outcome
Reinforcement will be assessed with the percentage of nicotine doses chosen during the Choice trials (out of 16), 4 choices per day over four days.
Conditions Studied
Interventions
- OTHER Saline
- DRUG Nicotine
Study Locations (1)
Connecticut
- VA Healthcare System - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2024-02-27 |
| Est. Completion | 2027-01-30 |
| Phase | Early Phase 1 |
What NCT06096714 shows while recruiting
NCT06096714 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (32% lower).
The record links to 1 condition, with Smoking Addiction appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT06096714 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06096714 about?
NCT06096714 is a clinical study titled "Addictive Threshold of Nicotine". To determine the nicotine threshold dose(s) for discrimination, subjective-rewarding effects, -and reinforcement in smokers with different levels of dependence.
What is the current status of trial NCT06096714?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 36 participants. The study started on 2024-02-27. Estimated completion is 2027-01-30.
What conditions does trial NCT06096714 study?
This clinical trial studies the following conditions: Smoking Addiction.
What interventions are being tested in trial NCT06096714?
The interventions under investigation include: Saline (OTHER), Nicotine (DRUG).
Who is sponsoring clinical trial NCT06096714?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06096714 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06096714's enrollment target sits among peer trials
36 712th of 2000 higher than 1,267 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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